Evidence map›Paper›PMID 41310006›Full record

ReviewNature reviews. Molecular cell biology2026

Critical constituents and assembly principles of centriole biogenesis in human cells.

Pierre Gönczy

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Molecular cell biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Pierre GönczySwiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland. pierre.gonczy@epfl.ch.ORCID http://orcid.org/0000-0002-6305-6883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The centriole is an evolutionarily conserved microtubule-bearing organelle with a striking 9-fold symmetrical architecture that is crucial for fundamental cellular processes in eukaryotes, including polarity, signalling and motility. The last two decades have witnessed important progress in uncovering the molecular architecture and assembly principles governing centriole biogenesis, which are discussed in this Review, with a focus on human cells. Recently developed advanced microscopy approaches have increased our understanding of the mechanisms governing centriole biogenesis, from initiating the assembly process to forming a full-fledged organelle. Some two billion years after its emergence during evolution, and more than 100 years after its identification by pioneering scientists, these advances make the centriole ripe for another era of discoveries.

Indexed as

CentriolesAnimalsHumansMicrotubules

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.