ArticleScientific reports2025
Differential role of anterior and posterior pituitary lobes in healthy aging and perceived stress.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Longitudinal MRI reveals adolescent pituitary growth patterns linked to puberty and environmental exposures.medRxiv : the preprint server for health sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The volume of the pituitary gland (PG) is impacted by both age and sex. However, their respective impact on the anterior and posterior lobes of the PG (APG and PPG) remains unclear, despite known distinctions in their neuroendocrinal roles. In this context, we investigated the impact of age and sex on the volume of each PG lobe across healthy adulthood. Lastly, we also tested whether perceived stress was influenced by the volumes of the APG and/or PPG and if the effects varied by age or sex. Results showed that older adults had a smaller APG but a larger PPG, compared to the younger adults. Women had a larger APG than men. Lastly, a main negative effect of PPG and an interaction between age-group and APG were reported on stress level, with the younger adults showing a negative association while the older adults had a positive association. Overall, we demonstrated that each PG lobe shows a different sex effect and age-related trajectory, with each having a different modulation on stress. This work underscores the need to examine the distinct roles of APG and PPG in the context of healthy and pathological aging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.