Evidence map›Paper›PMID 41309860›Full record

ArticleScientific reports2025

SplitWise regression for capturing nonlinear effects in interpretable model selection.

Marcell T Kurbucz, Nikolaos Tzivanakis, Nilufer Sari Aslam, Adam M Sykulski

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marcell T KurbuczInstitute for Global Prosperity, The Bartlett, University College London, 9-11 Endsleigh Gardens, London, WC1H 0EH, UK. m.kurbucz@ucl.ac.uk.
Nikolaos TzivanakisInstitute for Global Prosperity, The Bartlett, University College London, 9-11 Endsleigh Gardens, London, WC1H 0EH, UK.
Nilufer Sari AslamInstitute for Global Prosperity, The Bartlett, University College London, 9-11 Endsleigh Gardens, London, WC1H 0EH, UK.
Adam M SykulskiDepartment of Mathematics, Faculty of Natural Sciences, Imperial College London, 180 Queen's Gate, London, SW7 2AZ, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Capturing nonlinear relationships while maintaining interpretability remains a persistent challenge in regression modeling. We introduce SplitWise, a stepwise regression framework that adaptively transforms numeric predictors into threshold-based binary features using shallow decision trees-only when such transformations improve model fit according to the Akaike or Bayesian Information Criterion. This design preserves the transparency of linear models while flexibly capturing threshold-based nonlinear effects, positioning SplitWise between classical linear and interpretable nonlinear regression. SplitWise retains a single, globally linear equation that selectively incorporates data-driven thresholds-yielding models that remain straightforward to interpret and verify. Across synthetic scenarios with nonlinear signal patterns, SplitWise reduced median RMSE by 7-14% relative to the best-performing interpretable linear baseline and improved variable-selection accuracy (median Matthews Correlation Coefficient up to ∼0.79 vs. ∼0.51 for LASSO). On real datasets, SplitWise matched or slightly improved RMSE while selecting fewer predictors. For instance, on Wine Quality (White), it improved RMSE from 0.756 to 0.752 and on Wine Quality (Red) from 0.654 to 0.649, using 6-10 predictors. On Bodyfat, it achieved 3.48-3.49 RMSE with four predictors, comparable to Elastic Net (3.41-3.48 RMSE) but with smaller models.

Indexed as

Dummy variablesInterpretable modelingModel selectionSoftwareStepwise regressionThreshold effects

Identifiers

PMID41309860
PMCPMC12660875

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.