Evidence map›Paper›PMID 41309823›Full record

ArticleScientific reports2025

Unique response of polysulfide in serum albumin to oxidative stress.

Mayumi Ikeda-Imafuku, Maki Sakai, Keitaro Umezawa, Hidehiko Nakagawa, Toru Maruyama, Masaki Otagiri, Takaaki Akaike, Tomohiro Sawa, Ming Xian, Yuri Miura and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mayumi Ikeda-ImafukuDepartment of Physical Pharmaceutics, Wakayama Medical University, 25-1 Shichibancho, Wakayama, 640-8156, Japan. imayu@wakayama-med.ac.jp.
Maki SakaiInstitute of Biomedical Sciences, Tokushima University, 1-78-1 Sho-machi, Tokushima, 770-8505, Japan.
Keitaro UmezawaResearch Team for Mechanism of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo, 173-0015, Japan.
Hidehiko NakagawaGraduate School of Pharmaceutical Sciences, Nagoya City University, 3-1, Tanabe-dori, Mizuho-ku, Nagoya, Aichi, 467-8603, Japan.
Toru MaruyamaDepartment of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto, 862-0973, Japan.
Masaki OtagiriFaculty of Pharmaceutical Sciences, Sojo University, 4-22-1 Ikeda, Kumamoto, 860-0082, Japan.
Takaaki AkaikeDepartment of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.
Tomohiro SawaDepartment of Microbiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, 860-8556, Japan.
Ming XianDepartment of Chemistry, Brown University, Providence, RI, 02912, USA.
Yuri MiuraResearch Team for Mechanism of Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology, 35-2 Sakae-cho, Itabashi-ku, Tokyo, 173-0015, Japan.
Tatsuhiro IshidaInstitute of Biomedical Sciences, Tokushima University, 1-78-1 Sho-machi, Tokushima, 770-8505, Japan.
Yu IshimaLaboratory of Biopharmaceutics, Kyoto Pharmaceutical University, 5 Nakauchi-cho, Misasagi, Yamashina-ku, Kyoto, 607-8414, Japan. ishimayu@mb.kyoto-phu.ac.jp.

Funding

Japan Society for the Promotion of Science 21H02645Japan Society for the Promotion of Science 21H05267Japan Society for the Promotion of Science 23K17215
6 · The paper itself

Abstract

Supersulfide species have been identified as molecules that have catenated sulfur atoms as persulfides (R-SSH) and polysulfides (R-SS

Indexed as

Diabetic NephropathiesOxidative StressSerum AlbuminSulfidesAcute Kidney InjuryAnimalsAntioxidantsDisease Models, AnimalFemaleHumansMaleMiceMiddle AgedOxidation-ReductionSerum Albumin, HumanAntioxidantspolysulfideSerum AlbuminSerum Albumin, HumanSulfidesKidney diseaseOxidative stressPolysulfidesSerum albuminSupersulfides

Identifiers

PMID41309823
PMCPMC12663333

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.