Evidence map›Paper›PMID 41309613›Full record

ArticleNature communications2025

A non-monotonic code for event probability in the human brain.

Cedric Foucault, Tiffany Bounmy, Sébastien Demortain, Bertrand Thirion, Evelyn Eger, Florent Meyniel

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cedric Foucault *Cognitive Neuroimaging Unit, NeuroSpin (INSERM-CEA), University of Paris-Saclay, Gif-sur-Yvette, France. cedric.foucault@gmail.com.ORCID http://orcid.org/0000-0002-7247-6927
Tiffany Bounmy *Cognitive Neuroimaging Unit, NeuroSpin (INSERM-CEA), University of Paris-Saclay, Gif-sur-Yvette, France.
Sébastien DemortainCognitive Neuroimaging Unit, NeuroSpin (INSERM-CEA), University of Paris-Saclay, Gif-sur-Yvette, France.
Bertrand ThirionInria, CEA, University of Paris-Saclay, Palaiseau, France.ORCID http://orcid.org/0000-0001-5018-7895
Evelyn EgerCognitive Neuroimaging Unit, NeuroSpin (INSERM-CEA), University of Paris-Saclay, Gif-sur-Yvette, France.
Florent MeynielCognitive Neuroimaging Unit, NeuroSpin (INSERM-CEA), University of Paris-Saclay, Gif-sur-Yvette, France. florent.meyniel@cea.fr.ORCID http://orcid.org/0000-0002-6992-678X

Funding

Agence Nationale de la Recherche (French National Research Agency) ANR Grant #18-CE37-0010-01
6 · The paper itself

Abstract

Assessing probabilities and predicting future events are fundamental for perception and adaptive behavior, yet the neural representations of probability remain elusive. While previous studies have shown that neural activity in several brain regions correlates with probability-related factors such as surprise and uncertainty, similar correlations have not been found for probability. Here, using 7 Tesla functional magnetic resonance imaging, we uncover a representation of the probability of the next event in a sequence within the human dorsolateral prefrontal and intraparietal cortices. Crucially, univariate and multivariate analyses revealed that this representation employs a highly non-monotonic code. Tuning curves for probability exhibit selectivity to various probability ranges, while the code for confidence accompanying these estimates is predominantly monotonic. Given such diversity in tuning curves, future studies should move from assuming monotonic or simple canonical forms of tuning curves to considering richer representations, and clarify why different types of code exist.

Indexed as

BrainParietal LobeAdultBrain MappingFemaleHumansMagnetic Resonance ImagingMaleProbabilityYoung Adult

Identifiers

PMID41309613
PMCPMC12660876

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.