Evidence map›Paper›PMID 41309452›Full record

ArticleJournal of the American Chemical Society2025

Vinigrol Tricyclic Scaffold Biosynthesis Employs an Atypical Terpene Cyclase and a Multipotent Cyclization Cascade.

Kento Tsukada, Fumito Sato, Taro Matsuyama, Ryo Matsuda, Taro Ozaki, Yohei Morishita, Sho Furumura, Yuto Homma, Hikaru Sekiya, Akihiro Sugawara and 10 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Kento TsukadaGraduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Fumito SatoGraduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.ORCID 0009-0009-5912-2532
Taro MatsuyamaGraduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.ORCID 0009-0002-4138-7988
Ryo MatsudaGraduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Taro OzakiGraduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.ORCID 0000-0002-4673-4478
Yohei MorishitaGraduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.ORCID 0000-0001-8442-8642
Sho FurumuraGraduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Yuto HommaGraduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Hikaru SekiyaGraduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.
Akihiro SugawaraGraduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.ORCID 0000-0003-1266-7497
Masataka KubotaGraduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.
Takaaki MitsuhashiDivision of Advanced Molecular Science, Institute for Molecular Science (IMS), Okazaki, Aichi 444-8787, Japan.ORCID 0000-0001-7728-6869
Yoko YasunoGraduate School of Science, Osaka Metropolitan University, 3-3-138 Sugimoto, Sumiyoshi, Osaka 558-8585, Japan.ORCID 0000-0001-6725-8610
Tetsuro ShinadaGraduate School of Science, Osaka Metropolitan University, 3-3-138 Sugimoto, Sumiyoshi, Osaka 558-8585, Japan.ORCID 0000-0001-9145-1533
Ryuhei NagataGraduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.ORCID 0000-0002-2288-7111
Tomohisa KuzuyamaGraduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.ORCID 0000-0002-7221-5858
Tohru TaniguchiFrontier Research Center for Advanced Material and Life Science, Faculty of Advanced Life Science, Hokkaido University, North 21 West 11, Sapporo 001-0021, Japan.ORCID 0000-0002-4965-7383
Makoto FujitaDivision of Advanced Molecular Science, Institute for Molecular Science (IMS), Okazaki, Aichi 444-8787, Japan.ORCID 0000-0001-6105-7340
Masanobu UchiyamaGraduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan.ORCID 0000-0001-6385-5944
Teigo AsaiGraduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan.ORCID 0000-0002-8903-392X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vinigrol (

Indexed as

Alkyl and Aryl TransferasesDiterpenesCyclizationModels, MolecularMultigene FamilyAlkyl and Aryl TransferasesDiterpenesterpene synthase

Identifiers

PMID41309452
PMCPMC12703729

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.