Evidence map›Paper›PMID 41309363›Full record

ReviewJournal of microbiology and biotechnology2025

Governing Synthetic Biology: A Co-Evolutionary Framework for Sustainable Innovation.

Hyeonsu Kim, Jiyeon Lee, Yejin Cho, Haseong Kim, Heoung-Yeol Kim, Bong Hyun Sung

Abstract readReview
In one paragraph

Review in Journal of microbiology and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hyeonsu KimNational Biotechnology Policy Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.
Jiyeon LeeNational Biotechnology Policy Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.
Yejin ChoNational Biotechnology Policy Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.
Haseong KimSynthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.
Heoung-Yeol KimNational Biotechnology Policy Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.
Bong Hyun SungSynthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic biology has rapidly evolved from laboratory-based research to a core technology driving biomanufacturing, industrial innovation, and the global bioeconomy. Technological advancements such as next-generation sequencing, DNA synthesis, novel genome editing, and biofoundry automation are accelerating the industrial expansion and application of synthetic biology. However, despite these breakthroughs, current regulatory frameworks and societal acceptance are not in pace with technological development, creating significant barriers to the sustainable advancement of synthetic biology. This review offers a chronological analysis of synthetic biology development, examines regulatory and policy challenges, and proposes a 'co-evolutionary' model based on the 'Framework for Anticipatory Governance of Emerging Technologies' given by the Organization for Economic Co-operation and Development (OECD). Specifically, we highlight five key elements, research and development, strategic intelligence, societal trust formation, agile regulation, and international cooperation, as the foundation for mutual evolution of technology and institutional frameworks. Transforming science and technology into societal value requires essential policy support, which is a critical task for not only policymakers, but also scientists. Scientists must consider the societal context and institutional conditions in which their research operates, thereby ensuring the accountability and sustainability of science and technology. The future of synthetic biology requires a parallel approach that integrates scientific and technological advances with societal science perspectives, underpinned by collaborative governance among scientists, policymakers, and civil society.

Indexed as

InventionsSynthetic BiologyBiotechnologyHumansanticipatory governancebiomanufacturingregulatory governancesocietal acceptanceSynthetic biology

Identifiers

PMID41309363
PMCPMC12685586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.