Evidence map›Paper›PMID 41309265›Full record

ReviewBMJ open gastroenterology2025

Actionable mutations in pancreatic cancer: where targeted therapies are making a difference.

Morgan Fivaz, Aurélie Bornand, Claudia Corro, Thibaud Koessler, Vassilis Genoud

Abstract readReview
In one paragraph

Review in BMJ open gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Unravelling the pathogenesis and therapeutic approaches of pancreatic ductal adenocarcinoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Morgan FivazOncology Department, Geneva University Hospital, Geneva, Switzerland.
Aurélie BornandPathology Department, Geneva University Hospital, Geneva, Switzerland.
Claudia CorroOncology Department, Geneva University Hospital, Geneva, Switzerland.
Thibaud KoesslerOncology Department, Geneva University Hospital, Geneva, Switzerland.
Vassilis GenoudOncology Department, Geneva University Hospital, Geneva, Switzerland vassilis.genoud@hug.ch.ORCID http://orcid.org/0000-0001-5351-3043

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest solid tumours, with 5-year survival consistently below 10% and only modest gains from conventional chemotherapy after first-line failure. Although oncogenic

Indexed as

Carcinoma, Pancreatic DuctalMolecular Targeted TherapyPancreatic NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsHumansMutationPrecision MedicineANTIBODY TARGETED THERAPYGENE TARGETINGMUTATIONSPANCREATIC CANCER

Identifiers

PMID41309265
PMCPMC12666113

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.