Evidence map›Paper›PMID 41309211›Full record

ArticleJournal of epidemiology and community health2026

Cumulative poverty across early adulthood and midlife cognition: findings from the national longitudinal survey of youth.

Calvin L Colvin, Kaylie N Moropoulos, Xuexin Yu, Martine Elbejjani, M Maria Glymour, Adina Zeki Al Hazzouri, Katrina L Kezios

Abstract read
In one paragraph

Article in Journal of epidemiology and community health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Calvin L ColvinDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, New York, USA clc2266@columbia.edu.ORCID http://orcid.org/0000-0003-0323-2029
Kaylie N MoropoulosDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, New York, USA.
Xuexin YuDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, New York, USA.
Martine ElbejjaniClinical Research Institute, Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.
M Maria GlymourDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.
Adina Zeki Al HazzouriDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, New York, USA.
Katrina L KeziosDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, New York, USA.

Funding

Building an unbiased pooled cohort for the study of lifecourse social and vascular determinants of Alzheimer's Disease and Related DisordersR01AG072681 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GLYMOUR, MEDELLENA MARIA, ZEKI AL HAZZOURI, ADINA · 2021 to 2025
$4.0M
Investigating financial wellbeing, biological aging, and risk of Alzheimers disease and related dementias in a life course synthetic cohortR00AG084769 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Katrina L Kezios · 2025 to 2026
$489k
Investigating financial wellbeing, biological aging, and risk of Alzheimers disease and related dementias in a life course synthetic cohortK99AG084769 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KEZIOS, KATRINA L · 2024 to 2025
$263k
NIA NIH HHS K99 AG084769NIA NIH HHS R00 AG084769NIA NIH HHS R01 AG072681
6 · The paper itself

Abstract

introductionPrior studies have observed associations between poverty measured at single or across diffuse periods of the life course and cognitive function measured in later life. Few studies examine the relationship between cumulative poverty exposure and midlife cognition or address confounding of this relationship by early-life cognitive ability.

methodsTo estimate the effect of cumulative poverty with midlife cognitive function, we analysed data from National Longitudinal Survey of Youth 1979 participants with ≥3 family income measures over a 20-year period (1990-2010) who completed the modified Telephone Interview for Cognitive Status when ~48 years of age (N=2923). We defined participants' cumulative poverty status by the proportion of their family income measures <200% of the Federal Poverty Limit: 0 (never), <1/3 but >0 (sometimes), ≥1/3 but less than all (often) and all (always). Armed Forces Qualification Test score defined early-life cognitive ability. We used linear regression models to examine the association between cumulative poverty and sample-standardised z-scores for memory, attention and global cognitive function.

resultsOverall, 37.9% of participants were never, 26.6% were sometimes, 27.5% were often and 8.0% were always in poverty. In fully adjusted models and relative to participants never in poverty, those often (beta: -0.13; 95% CI -0.23 to -0.04) and always (beta: -0.37; 95% CI -0.53 to -0.22) in poverty had lower z-scores for midlife global cognitive function. Likewise, their z-scores were lower for midlife memory function.

conclusionsLonger durations of poverty exposure may be more detrimental for midlife cognition. This relationship was not fully explained by early-life cognitive ability.

Indexed as

CognitionPovertyAdolescentAdultFemaleHumansLongitudinal StudiesMaleMiddle AgedUnited StatesYoung AdultCOGNITIONDEMENTIALife course epidemiologyLONGITUDINAL STUDIESPOVERTY

Identifiers

PMID41309211
PMCPMC12890565

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.