ArticleVox sanguinis2026
In vitro quality assessment of red blood cells and plasma units in DEHT/SAGM bags and DEHT/PAGGSM bags during storage.
Article in Vox sanguinis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- In vitro evaluation of apheresis platelet and plasma products collected and stored in non-DEHP disposable sets.Vox sanguinis · 2026Trial
- Bacterial proliferation is comparable in red blood cell concentrates stored in DEHT/PAGGSM and DEHP/SAGM containers.Vox sanguinis · 2026Article
- In vitro quality assessment of red blood cells and plasma units in DEHT/SAGM bags and DEHT/PAGGSM bags during storage.Vox sanguinis · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
BACKGROUND AND
objectivesDEHT is considered a safer alternative to DEHP, a commonly used plasticizer with potential toxicological risks. We aimed to compare the storage efficacy of red blood cells (RBCs) in DEHT bags containing two different additive solutions: SAGM and PAGGSM. A second objective was to evaluate the effect of transport/later processing in France (Etablissement Français du Sang [EFS]) on Day 1 versus early processing/transport in Belgium (Service Francophone du Sang [SFS]) on Day 0 before storage on the quality of blood components. MATERIALS AND
methodsRBC quality, including haemolysis and supernatant metabolic parameters, as well as plasma quality parameters, was measured over a period of 49 days and 2 years for RBC and plasma, respectively.
resultsRBCs stored in DEHT/PAGGSM bags showed superior quality preservation compared to those stored in DEHT/SAGM bags, with lower haemolysis rates (p < 0.01 for EFS and p < 0.05 for SFS) at the end of storage and better preserved adenosine triphosphate (ATP) levels over time at the EFS site (p < 0.01). No significant differences were observed in the measured plasma quality parameters.
conclusionDEHT blood bags combined with PAGGSM additive solution are a promising and safer alternative to DEHP/SAGM bags for RBC storage. The DEHT/PAGGSM combination results in improved preservation of RBC quality and stores plasma units adequately, compared to the DEHT/SAGM combination. Our take-home message is that processing and transport times which mimic routine practices for blood centres that are distant from collection sites do not affect the quality of blood components stored in DEHT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.