Evidence map›Paper›PMID 41309100›Full record

Observational studyJournal of medical Internet research2025

AI-Enhanced Social Robotic Versus Computer-Based Virtual Patients for Clinical Reasoning Training in Medical Education: Observational Crossover Cohort Study.

Alexander Borg, Jonathan Schiött, William Ivegren, Cidem Gentline, Viking Huss, Anna Hugelius, Benjamin Jobs, Fabricio Espinosa, Mini Ruiz, Samuel Edelbring and 3 more

Abstract readObservational StudyComparative Study
In one paragraph

Observational study in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alexander BorgDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, and Center for Molecular Medicine (CMM), Stockholm, Sweden.ORCID 0000-0003-1013-4590
Jonathan SchiöttDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, and Center for Molecular Medicine (CMM), Stockholm, Sweden.ORCID 0009-0001-0445-630X
William IvegrenDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, and Center for Molecular Medicine (CMM), Stockholm, Sweden.ORCID 0009-0004-8417-6106
Cidem GentlineDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, and Center for Molecular Medicine (CMM), Stockholm, Sweden.ORCID 0009-0000-1903-5826
Viking HussDivision of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.ORCID 0000-0002-9764-6435
Anna HugeliusDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, and Center for Molecular Medicine (CMM), Stockholm, Sweden.ORCID 0009-0003-0903-9569
Benjamin JobsDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, and Center for Molecular Medicine (CMM), Stockholm, Sweden.ORCID 0009-0002-2391-8087
Fabricio EspinosaDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, and Center for Molecular Medicine (CMM), Stockholm, Sweden.ORCID 0000-0001-6227-8209
Mini RuizDepartment of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-9910-8809
Samuel EdelbringSchool of Education, Culture and Communication, Mälardalen University, Västerås, Sweden.ORCID 0000-0002-1110-0782
Carina GeorgDepartment of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-8444-7624
Gabriel SkantzeDivision of Speech Music and Hearing, Royal Institute of Technology (KTH), Stockholm, Sweden.ORCID 0000-0002-8579-1790
Ioannis ParodisDivision of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, and Center for Molecular Medicine (CMM), Stockholm, Sweden.ORCID 0000-0002-4875-5395

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVirtual patient (VP) simulations can be used to practice clinical reasoning (CR) in controlled learning environments. Traditional computer-based VP platforms often lack the authenticity and interactivity required for effective CR training. Artificial intelligence (AI)-enhanced social robotic VPs can enhance realism and engagement; however, quantitative evidence comparing them with conventional VP platforms remains limited.

objectiveWe compared medical students' experience of an AI-enhanced social robotic versus a conventional computer-based VP platform regarding the extent to which the design characteristics of the respective platform facilitate CR skill training.

methodsThis observational crossover cohort study involved 178 sixth-semester medical students at Karolinska Institutet, Stockholm, Sweden (response rate: 42.3%; 178 of 421 invited students; Spring 2024-Spring 2025), who experienced both a large language model-enhanced social robotic VP platform supporting dialogue (social artificial intelligence-enhanced robotic interface [SARI]) and a conventional computer-based VP platform (virtual interactive case [VIC]) during their clinical rotation within rheumatology. Platform order was determined by clinical rotation scheduling. VP design was evaluated using a validated questionnaire across 5 domains: authenticity, professional approach, coaching quality, learning effects, and overall judgment. Students' CR training preferences were assessed using categorical responses and a Visual Analogue Scale, where a lower score favored SARI and a score of 5 indicated equal preference between platforms.

resultsSARI outperformed VIC across all 5 VP design domains. Students rated SARI higher for authenticity (median 4.0, IQR 3.5-4.5 vs 3.0, IQR 2.5-3.5; P<.001), professional approach (median 4.5, IQR 4.0-4.8 vs 4.0, IQR 3.5-4.5; P<.001), coaching quality (median 4.3, IQR 4.0-4.7 vs 4.0, IQR 3.7-4.7; P<.001), learning effect (median 4.4, IQR 4.0-5.0 vs 4.0, IQR 3.5-4.5; P<.001), and overall judgment (median 5.0, 4.0-5.0 vs 4.0, IQR 4.0-5.0; P<.001). Students strongly preferred SARI for CR training (72% vs 14%; odds ratio [OR] 27.1, 95% CI 14.3-53.7; P<.001), with Visual Analogue Scale scores confirming this preference (median 3.0, IQR 2.0-5.0; P<.001). Preferences were consistent across most subgroups (sex, prior VP experience, and platform order); in 2 subgroups, the difference was not significant, that is, students with prior VP experience (62% vs 38%; OR 2.6; 95% CI 0.8-8.9; P=.11) and students first introduced to VIC (55% vs 45%; OR 1.5; 95% CI 0.7-2.9; P=.33).

conclusionsOur findings provide the first quantitative evidence that AI-enhanced social robotic VPs offer superior design characteristics than conventional computer-based platforms for CR training in medical education. These results support the use of AI-driven social robots for VP simulations to better prepare medical students for real clinical encounters, and warrant future research on objective CR skill outcomes and long-term transfer to clinical practice. Unlike previous qualitative studies examining each platform separately, this study provides the first quantitative comparison of design characteristics between AI-enhanced social robotic and conventional computer-based VPs.

Indexed as

Artificial IntelligenceClinical ReasoningEducation, MedicalRoboticsAdultCohort StudiesCross-Over StudiesFemaleHumansMaleStudents, MedicalSurveys and QuestionnairesSwedenartificial intelligenceclinical reasoningeducational technologylarge language modelsmedical educationsocial roboticsvirtual patients

Identifiers

PMID41309100
PMCPMC12699248

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.