In one paragraphArticle in American journal of physiology. Gastrointestinal and liver physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors.
Travis M WalrathDivision of GI, Trauma and Endocrine Surgery, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0000-0002-7236-1388 Mara R EvansDivision of GI, Trauma and Endocrine Surgery, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0009-0002-5111-6313 Kenneth Meza MongeDivision of GI, Trauma and Endocrine Surgery, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0000-0001-5509-5148 Kevin M NajarroDivision of GI, Trauma and Endocrine Surgery, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.
David J OrlickyDepartment of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0000-0002-0417-1400 Juan-Pablo IdrovoDivision of GI, Trauma and Endocrine Surgery, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.
Rachel H McMahanDivision of GI, Trauma and Endocrine Surgery, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0000-0003-2162-2821 Elizabeth J KovacsDivision of GI, Trauma and Endocrine Surgery, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0000-0002-9459-9928 Funding
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI JANINE A HIGGINS · 1995 to 2026
$32.6MUniversity of Colorado Aging Training GrantT32AG000279 · NIA · UNIVERSITY OF COLORADO DENVER · PI Kerrie Moreau · 2001 to 2026
$10.1MAging, macrophage mediators, and burn trauma: SupplementR01AG018859 · NIA · UNIVERSITY OF COLORADO DENVER · PI KOVACS, ELIZABETH J. · 2001 to 2024
$7.6MAging, Burn Trauma, and Liver DamageR01GM153949 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI Juan Pablo Idrovo · 2024 to 2026
$1.0MGut-brain axis at the intersection of aging and traumatic injuryF32AG082443 · NIA · UNIVERSITY OF COLORADO DENVER · PI WALRATH, TRAVIS MICHAEL · 2023 to 2024
$95kNIA NIH HHS F32 AG082443NIA NIH HHS R01 AG018859NIA NIH HHS T32 AG000279NIDDK NIH HHS P30 DK048520NIGMS NIH HHS R01 GM153949
6 · The paper itselfAbstract
The global population is aging, with one in six people projected to be 65 yr or older by 2050. Since people aged 65 and older experience higher rates of morbidity and mortality after burn injury, there is an increased need to develop effective burn treatments in this age group. Heightened morbidity and risk of mortality may stem from increased gut leakiness and death of intestinal epithelial cells of aged individuals. Herein, we used our clinically relevant model of scald burn injury in young and aged mice to ascertain whether the colon, isolated colonic epithelium, and organoids grown from the colon have deficiencies in cell growth, senescence, and apoptosis pathways. Aged, burn-injured mice displayed increased senescence marker
Indexed as
AgingBurnsCell ProliferationCellular SenescenceColonIntestinal MucosaAnimalsApoptosisCyclin-Dependent Kinase Inhibitor p16Disease Models, AnimalMaleMiceMice, Inbred C57BLReceptors, G-Protein-CoupledCdkn2a protein, mouseCyclin-Dependent Kinase Inhibitor p16Lgr5 protein, mouseReceptors, G-Protein-Coupledapoptosisinflammagingorganoidproliferationsenescence
Identifiers
PMID41309057
PMCPMC12797342
What OpenQuestion holds
Textmetadata
LicenceTDM
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