Evidence map›Paper›PMID 41308797›Full record

Trial reportRespiratory medicine2025

Determinants of balance impairment in individuals with Chronic Obstructive Pulmonary Disease: A secondary analysis of a randomized controlled trial.

Hassan Alrabbaie, Marla Beauchamp, Cindy Ellerton, Roger Goldstein, Annemarie L Lee, Jennifer A Alison, Gail Dechman, Kimberley J Haines, Samantha L Harrison, Anne E Holland and 5 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Respiratory medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hassan AlrabbaieSchool of Rehabilitation Sciences, Faculty of Health Science, McMaster University, Canada; Department of Rehabilitation Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid, Jordan. Electronic address: alrabbah@mcmaster.ca.
Marla BeauchampSchool of Rehabilitation Sciences, Faculty of Health Science, McMaster University, Canada. Electronic address: beaucm1@mcmaster.ca.
Cindy EllertonDepartment of Respiratory Medicine, West Park Healthcare Centre, Toronto, Canada; Department of Physical Therapy, Faculty of Medicine, University of Toronto, Toronto, ON, Canada. Electronic address: c.ellerton@utoronto.ca.
Roger GoldsteinDepartment of Respiratory Medicine, West Park Healthcare Centre, Toronto, Canada; Department of Physical Therapy, Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Rehabilitation Sciences Institute, School of Graduate Studies, University of Toronto, Toronto, ON, Canada. Electronic address: roger.goldstein@uhn.ca.
Annemarie L LeeInstitute for Breathing and Sleep, Melbourne, VIC, Australia; Department of Physiotherapy, School of Primary and Allied Health Care, Monash University, Melbourne, VIC, Australia. Electronic address: annemarie.lee@monash.edu.
Jennifer A AlisonSchool of Health Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia; Allied Health, Sydney Local Health District, Sydney, Australia. Electronic address: jennifer.alison@sydney.edu.au.
Gail DechmanSchool of Physiotherapy, Faculty of Health, Dalhousie University, Halifax, NS, Canada. Electronic address: gail.dechman@dal.ca.
Kimberley J HainesPhysiotherapy Department, Western Health, Department of Critical Care, The University of Melbourne, Melbourne, VIC, Australia. Electronic address: kimberley.haines@wh.org.au.
Samantha L HarrisonSchool of Health and Life Sciences, Teesside University, Middlesbrough, UK. Electronic address: s.l.harrison@tees.ac.uk.
Anne E HollandInstitute for Breathing and Sleep, Melbourne, VIC, Australia; Department of Physiotherapy, Alfred Health, Melbourne, VIC, Australia; Respiratory Research, Monash University, Melbourne, VIC, Australia. Electronic address: anne.holland@monash.edu.
Alda MarquesLab3R-Respiratory Research and Rehabilitation Laboratory, School of Health Sciences (ESSUA), Institute of Biomedicine (iBiMED), University of Aveiro, Aveiro, Portugal. Electronic address: amarques@ua.pt.
Lissa SpencerSchool of Health Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia; Department of Physiotherapy, Royal Prince Alfred Hospital, Camperdown, NSW, Australia. Electronic address: lissa.spencer@health.nsw.gov.au.
Michael K SticklandDivision of Pulmonary Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada; G.F. MacDonald Centre for Lung Health, Covenant Health, Edmonton, AB, Canada. Electronic address: michael.stickland@ualberta.ca.
Elizabeth H SkinnerDepartment of Physiotherapy, School of Primary and Allied Health Care, Monash University, Melbourne, VIC, Australia; Physiotherapy Department, Western Health, Department of Critical Care, The University of Melbourne, Melbourne, VIC, Australia. Electronic address: drlizzieskinner@gmail.com.
Dina BrooksSchool of Rehabilitation Sciences, Faculty of Health Science, McMaster University, Canada; Department of Respiratory Medicine, West Park Healthcare Centre, Toronto, Canada; Department of Physical Therapy, Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Rehabilitation Sciences Institute, School of Graduate Studies, University of Toronto, Toronto, ON, Canada. Electronic address: brookd8@mcmaster.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBalance impairment is common in individuals with Chronic Obstructive Pulmonary Disease (COPD), increasing fall risk and reducing functional independence. This study investigated functional, clinical, and demographic determinants of balance performance in individuals with COPD.

methodsThis secondary analysis included participants from a randomized controlled trial involving pulmonary rehabilitation centers. Balance was evaluated using the Berg Balance Scale (BBS) and Balance Evaluation Systems Test (BESTest). Functional assessments comprised the 30-Second Chair Stand Test (30s CST) and Six-Minute Walk Test (6-MWT). Clinical variables included lung function, dyspnea, comorbidities, medications, fall history, supplemental oxygen, and gait aid use. Multiple regression analyses were conducted to evaluate associations between balance, functional, clinical, and demographic factors.

resultsOf the 244 participants (mean age: 71 ± 9 years; 57 % male), 87 % reported balance deficits and 50 % had at least one fall in the past year. Functional capacity was strongly correlated with balance scores (r > 0.5, p < 0.001). Clinical factors, including dyspnea, comorbidities, gait aid, and supplemental oxygen use, were also significant. The full regression model explained 58 % of the variance in BESTest scores and 51 % in BBS scores. Each additional 30s CST repetition predicted a 1.22-point increase in BESTest scores and a 0.59-point increase in BBS scores. Less severe dyspnea was associated with higher scores on both balance measures.

conclusionBalance performance in individuals with COPD is influenced by both clinical and functional parameters. Identification of these factors supports the development of targeted interventions to address balance impairment and improve patient outcomes in this population.

Indexed as

Postural BalancePulmonary Disease, Chronic ObstructiveAccidental FallsAgedAged, 80 and overDyspneaFemaleHumansMaleMiddle AgedWalk TestBalanceCOPDDyspneaExercise capacityFallsFunctional performance

Identifiers

PMID41308797
PMCPMC12706577

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.