ArticleCell reports. Medicine2025
L-Phenylalanine is a metabolic checkpoint of human Th2 cells.
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Article in Cell reports. Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5citing papers in PubMed
–field-weighted citation impact
What it found
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Who cites it
5 citing papers in PubMed.
- Bridging Rare to Common Diseases: Precision Medicine and the Transforming Landscape of Pediatric Allergy and Immunology.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026Review
- Polysaccharides from Er Chen Decoction: gastrointestinal fate, gut microbiota modulation and metabolomics.Frontiers in microbiology · 2026Article
- Phenylalanine homeostasis in metabolic disorders: epidemiological trends, pathophysiological mechanisms, and clinical treatment.Frontiers in endocrinology · 2026Review
- Uncovering protein prenylation in Th1 cells: novel prenylation sites and insights into statin and farnesyltransferase inhibition.BMC biology · 2025Article
- Metabolic regulation of Th17/Treg balance.Central-European journal of immunology · 2025Article
Corrections and comments
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Authors and funding
30 authors.
Abhijeet J KulkarniSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Juan Rodriguez-CoiraSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland; Departamento de Ciencias Médicas Básicas, Facultad de Medicina, Instituto de Medicina Molecular Aplicada - Nemesio Díez (IMMA-ND), Universidad San Pablo-CEU, CEU Universities, Madrid, Spain; Centro de Metabolómica y Bioanálisis (CEMBIO), Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte 28660, Spain.
Nino StockerSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Urszula RadzikowskaSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Antonio J García-CívicoDepartamento de Ciencias Médicas Básicas, Facultad de Medicina, Instituto de Medicina Molecular Aplicada - Nemesio Díez (IMMA-ND), Universidad San Pablo-CEU, CEU Universities, Madrid, Spain; Centro de Metabolómica y Bioanálisis (CEMBIO), Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte 28660, Spain.
María Isabel Delgado DolsetDepartamento de Ciencias Médicas Básicas, Facultad de Medicina, Instituto de Medicina Molecular Aplicada - Nemesio Díez (IMMA-ND), Universidad San Pablo-CEU, CEU Universities, Madrid, Spain; Centro de Metabolómica y Bioanálisis (CEMBIO), Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte 28660, Spain.
Nuria ContrerasDepartamento de Ciencias Médicas Básicas, Facultad de Medicina, Instituto de Medicina Molecular Aplicada - Nemesio Díez (IMMA-ND), Universidad San Pablo-CEU, CEU Universities, Madrid, Spain; Centro de Metabolómica y Bioanálisis (CEMBIO), Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte 28660, Spain.
Inés Jardón ParagesSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Vanesa Saiz SanchezUGC Immunología y Alergia, Hospital Universitario Reina Sofía de Córdoba, Córdoba, Spain; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)/Hospital Universitario Reina Sofía/Universidad de Córdoba, Córdoba, Spain.
Pilar SerranoUGC Immunología y Alergia, Hospital Universitario Reina Sofía de Córdoba, Córdoba, Spain; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)/Hospital Universitario Reina Sofía/Universidad de Córdoba, Córdoba, Spain.
Elena IzquierdoDepartamento de Ciencias Médicas Básicas, Facultad de Medicina, Instituto de Medicina Molecular Aplicada - Nemesio Díez (IMMA-ND), Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.
Cristina Gomez-CasadoDepartamento de Ciencias Médicas Básicas, Facultad de Medicina, Instituto de Medicina Molecular Aplicada - Nemesio Díez (IMMA-ND), Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.
Javier Sanchez-SolaresDepartamento de Ciencias Médicas Básicas, Facultad de Medicina, Instituto de Medicina Molecular Aplicada - Nemesio Díez (IMMA-ND), Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.
Carmela Pablo-TorresDepartamento de Ciencias Médicas Básicas, Facultad de Medicina, Instituto de Medicina Molecular Aplicada - Nemesio Díez (IMMA-ND), Universidad San Pablo-CEU, CEU Universities, Madrid, Spain; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
David ObesoDepartamento de Ciencias Médicas Básicas, Facultad de Medicina, Instituto de Medicina Molecular Aplicada - Nemesio Díez (IMMA-ND), Universidad San Pablo-CEU, CEU Universities, Madrid, Spain; Centro de Metabolómica y Bioanálisis (CEMBIO), Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte 28660, Spain.
Carmen Moreno-AguilarUGC Immunología y Alergia, Hospital Universitario Reina Sofía de Córdoba, Córdoba, Spain; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)/Hospital Universitario Reina Sofía/Universidad de Córdoba, Córdoba, Spain.
Maria Luisa EspinazoUGC Immunología y Alergia, Hospital Universitario Reina Sofía de Córdoba, Córdoba, Spain; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)/Hospital Universitario Reina Sofía/Universidad de Córdoba, Córdoba, Spain.
Andrzej EljaszewiczCentre of Regenerative Medicine, Medical University of Bialystok, ul. Waszyngtona 15B, 15-269 Bialystok, Poland; Tissue and Cell Bank, Medical University of Bialystok Clinical Hospital, Bialystok, Poland.
Jana KochSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland; Institute of Theoretical Medicine, University of Augsburg, Augsburg, Germany.
Katja BaerenfallerSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Anja HeiderSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
Ge TanSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland; Functional Genomics Center Zurich, ETH Zurich/University of Zurich, Zurich, Switzerland.
Damir ZhakparovSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
Maria M EscribeseDepartamento de Ciencias Médicas Básicas, Facultad de Medicina, Instituto de Medicina Molecular Aplicada - Nemesio Díez (IMMA-ND), Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.
Berta Ruiz-LeonUGC Immunología y Alergia, Hospital Universitario Reina Sofía de Córdoba, Córdoba, Spain; Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)/Hospital Universitario Reina Sofía/Universidad de Córdoba, Córdoba, Spain.
Cezmi A AkdisSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland; Christine Kühne - Center for Allergy Research and Education (CK-CARE), Davos, Graubünden, Switzerland.
Rafael J ArgüelloAix Marseille University, CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France.
Domingo BarberDepartamento de Ciencias Médicas Básicas, Facultad de Medicina, Instituto de Medicina Molecular Aplicada - Nemesio Díez (IMMA-ND), Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.
Alma VillaseñorDepartamento de Ciencias Médicas Básicas, Facultad de Medicina, Instituto de Medicina Molecular Aplicada - Nemesio Díez (IMMA-ND), Universidad San Pablo-CEU, CEU Universities, Madrid, Spain; Centro de Metabolómica y Bioanálisis (CEMBIO), Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte 28660, Spain.
Milena SokolowskaSwiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland. Electronic address: milena.sokolowska@siaf.uzh.ch.
Funding
No grant is acknowledged in the PubMed record.
Abstract
After the primary response, circulating memory CD4
Indexed as
PhenylalanineTh2 CellsCell DifferentiationCell ProliferationEnergy MetabolismGlycolysisHumansHypersensitivityLarge Neutral Amino Acid-Transporter 1Oxidative PhosphorylationSignal TransductionSTAT6 Transcription FactorTh17 CellsT-Lymphocytes, RegulatoryTOR Serine-Threonine KinasesLarge Neutral Amino Acid-Transporter 1PhenylalanineSTAT6 protein, humanSTAT6 Transcription FactorTOR Serine-Threonine Kinasesallergyamino acidasthmaCD4+T cellimmunometabolismmetabolomicsphenylalanineregulatory T cellssingle-cell energy metabolismTh2 cells
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.