ReviewBioscience reports2025
An overview of vital functions of human ecdysoneless (ECD), a highly conserved protein.
Review in Bioscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Human ecdysoneless (ECD), the human ortholog of Ecd protein of Drosophila melanogaster, is a highly conserved protein. This protein comprises a well-folded N-terminal domain and a disordered C-terminal domain; these domains interact with multiple proteins and are involved in diverse biological processes, including cell cycle regulation, transactivation, pre-mRNA splicing, and glucose metabolism. ECD is highly expressed in various cancers, and its elevated expression is associated with poor prognosis in several types of human cancers. Therefore, it can serve as a potential biomarker and therapeutic target for treating tumors. This review focuses on the currently available knowledge of the physiological and pathological functions of ECD; moreover, the directions of prospective research in the relevant field have been discussed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.