Observational studyDigestive diseases and sciences2026
A Comparative Study on Quality of Life Between Primary Early Surgery and Late Surgery in Chronic Calcific Pancreatitis using the SF-36 Questionnaire-A Prospective Observational Cohort Study.
Observational study in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Feasibility randomized controlled trial of a home-based support program for family caregivers of people with Alzheimer's disease.Frontiers in aging neuroscience · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aim to test the hypothesis that "primary early surgery (i.e., within 2 years from symptoms onset) in chronic calcific pancreatitis (CCP) has better durable long-term Quality of Life (QOL) than patients undergoing late surgery (> 2 years from symptom onset)" using the SF-36 questionnaire.
methodsThis is a prospective observational study conducted between 2016 and 2025. 162 patients with large-duct CCP (MPD diameter ≥ 6 mm) underwent either Frey's procedure or lateral pancreatico-jejunostomy (LPJ). 62/162 patients on regular follow -up were included in the study. The 62 patients were grouped into primary early surgery group (PESG) and late surgery group (LSG). After long term (> 3 year) of follow-up, patient's responses regarding QOL were recorded using the SF-36 questionnaire and compared. The primary outcome measures were pain, physical functioning and role limitations due to physical health and the other components on the SF-36 were taken as secondary outcome measures.
results27/62 cases were in LSG and 35/62 belonged to PESG. Mann-Whitney U test was used to make group comparisons. 7 out of 8 components namely Pain, Physical Functioning, Role Limitations Due to Physical Health, Role Limitations Due to Emotional Problems, Energy/ Fatigue, Emotional Well-Being, Social Functioning had statistically significant difference favoring better QOL in PESG.
conclusionPrimary early surgery has a positive impact on long-term QOL in patients with CCP. However, future RCTs will help to draw solid conclusions to support or refute our observations.
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