Evidence map›Paper›PMID 41307802›Full record

ReviewCurrent cardiology reports2025

Microplastics and Cardiovascular Disease: Should Clinicians Be Paying Attention?

Pedro Rafael Vieira de Oliveira Salerno, Ricardo J Estrada-Mendizabal, Coral Lozada, Sarju Ganatra, Mohamed Bassiony, Omar Aboukhatwa, Colin Carpenter, Sadeer Al-Kindi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pedro Rafael Vieira de Oliveira SalernoDepartment of Medicine, NYC Health & Hospitals/Elmhurst, Icahn School of Medicine at Mount Sinai, New York , Queens, USA.
Ricardo J Estrada-MendizabalDepartment of Medicine, NYC Health & Hospitals/Elmhurst, Icahn School of Medicine at Mount Sinai, New York , Queens, USA.
Coral LozadaOffice of Sustainability, Houston Methodist, Houston, TX, USA.
Sarju GanatraDivision of Cardiovascular Medicine, Department of Medicine, Lahey Hospital & Medical Center, Beth Israel Lahey Health, Burlington, MA, USA.
Mohamed BassionyDepartment of Medicine, NYC Health & Hospitals/Elmhurst, Icahn School of Medicine at Mount Sinai, New York , Queens, USA.
Omar AboukhatwaDepartment of Medicine, NYC Health & Hospitals/Elmhurst, Icahn School of Medicine at Mount Sinai, New York , Queens, USA.
Colin CarpenterDepartment of Medicine, NYC Health & Hospitals/Elmhurst, Icahn School of Medicine at Mount Sinai, New York , Queens, USA.
Sadeer Al-KindiCenter for Cardiovascular Prevention & Wellness, Houston Methodist, Houston, TX, USA. sal-kindi@houstonmethodist.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo provide clinicians with a concise introduction of microplastics potential role as a cardiovascular risk factor. RECENT

findingsMicroplastics have been identified in human cardiovascular tissues. In vitro and animal-based studies associate microplastics presence with increased oxidative stress, endothelial dysfunction, platelet aggregation disruption, and low-grade inflammation. Small human studies report associations between intraplaque or circulating microplastics and cardiovascular outcomes. However, these signals are associative, method-dependent, and vulnerable to exposure misclassification, co-pollutant confounding, contamination, and heterogeneous analytics. Microplastics are pervasive and biologically plausible as a cardiovascular risk factor, supported by growing in-vitro evidence and incipient human association studies. Cohesive population-level measures to curb MP pollution should be embedded within policies addressing broader environmental cardiovascular risk factors. For clinicians, it remains premature to recommend personal-level mitigation strategies, and MPs are best regarded as an emerging exposure within the patient's exposome that warrants awareness and further rigorous studies.

Indexed as

Cardiovascular DiseasesEnvironmental ExposureMicroplasticsAnimalsHeart Disease Risk FactorsHumansOxidative StressRisk FactorsMicroplasticsCardiologyEnvironmentEpidemiologyMechanismsMicroplastics

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.