Evidence map›Paper›PMID 41307713›Full record

ReviewHNO2025

S3 guidelines on thyroid carcinoma: what's new? : Comparison of current and previous recommendations on diagnosis and surgery.

Lukas Kuczera, Sarina Katrin Müller, Matti Sievert

Abstract readReview
PubMed Publisher
In one paragraph

Review in HNO, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lukas KuczeraDepartment of Otorhinolaryngology, Head and Neck Surgery, Erlangen University Hospital, Waldstrasse 1, 91054, Erlangen, Germany.
Sarina Katrin MüllerDepartment of Otorhinolaryngology, Head and Neck Surgery, Erlangen University Hospital, Waldstrasse 1, 91054, Erlangen, Germany.
Matti SievertDepartment of Otorhinolaryngology, Head and Neck Surgery, Erlangen University Hospital, Waldstrasse 1, 91054, Erlangen, Germany. matti.sievert@uk-erlangen.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDue to their high prevalence the management of thyroid nodules requires a particularly systematic approach. If the diagnostics reveal a suspected or confirmed thyroid cancer, in most cases surgical treatment remains the primary treatment option.

objectiveThe aim of this work is to provide an overview of the guideline-based approach to thyroid nodules and carcinomas with a focus on diagnostics and surgical treatment. The essential differences in content between the previous and current guidelines are identified. MATERIAL AND

methodsSelection of the most practice-relevant recommendations of the guidelines on thyroid cancer published in 2025 and comparison of these with the recommendations of the guidelines on surgical treatment of malignant thyroid diseases published in 2012.

resultsThe new guidelines are significantly more comprehensive and detailed. The recommended diagnostic procedure is more precise and supplemented by examination techniques such as elastography. The surgical procedure keeps its role as the primary treatment approach. In accordance with the current study situation new options, such as the observational behavior for papillary microcarcinomas under defined conditions, are included. The recommendations on the diagnostics and treatment of undifferentiated thyroid cancer have been substantially expanded.

conclusionThe new guidelines provide a comprehensive overview of the diagnostics and treatment of thyroid cancer and expands on the previous guidelines with consideration of the current study situation.

Indexed as

DiagnosticsGlandular and epithelial neoplasmsGuidelinesThyroid noduleTreatment

Identifiers

PMID41307713

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.