Evidence map›Paper›PMID 41307645›Full record

ArticleFolia microbiologica2025

Characterization of novel lactic acid bacteria from Algerian ecosystems with probiotic potential and antioxidant-antidiabetic properties.

Abdelkader Mahrouk, Asma Mosbah, Noreddine Kacem Chaouche, Mahdi Hamdi, Abdelkader Slimani, Mohamed Yahia Zeriab Badaoui, Yassine Amrani, Salah Akkal

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Article in Folia microbiologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abdelkader MahroukLaboratory of Applied Biochemistry, Faculty of Natural and Life Sciences, University Constantine 1, Constantine, 25000, Algeria.
Asma MosbahLaboratory of Applied Biochemistry, Faculty of Natural and Life Sciences, University Constantine 1, Constantine, 25000, Algeria.
Noreddine Kacem ChaoucheLaboratory of Mycology, Biotechnology and Microbial Activity (LaMyBAM), University of Constantine 1, Constantine, Constantine, 25000, Algeria.
Mahdi HamdiBiotechnology Research Center (CRBt), Ali Mendjli Nouvelle Ville UV 03 BP E73, Constantine, 25016, Algeria.
Abdelkader SlimaniUnit of the Valorization of Natural Resources, Bioactive Molecules and Physicochemical and Biological Analysis, Faculty of Exact Sciences, University Constantine 1, Constantine, 25000, Algeria.
Mohamed Yahia Zeriab BadaouiLaboratory of Applied Biochemistry, Faculty of Natural and Life Sciences, University Constantine 1, Constantine, 25000, Algeria.
Yassine AmraniDepartment of Infection, Immunity and Inflammation, Leicester, National Institute for Health Research, Leicester Biomedical Research Centre Respiratory, Glenfield Hospital, Groby Road, Leicester, LE3 9QP, UK.
Salah AkkalUnit of the Valorization of Natural Resources, Bioactive Molecules and Physicochemical and Biological Analysis, Faculty of Exact Sciences, University Constantine 1, Constantine, 25000, Algeria. salah.akkal@umc.edu.dz.ORCID http://orcid.org/0000-0002-4999-5673

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current investigation aimed to highlight the potential of probiotics isolated from lactic acid bacteria of different Algerian ecosystems as antioxidant and antidiabetic agents. Fifty-four strains from different ecosystems were isolated anaerobically. The subsequent steps involved comprehensive characterization and in vitro assessments, including assays for scavenging DPPH and ABTS•+ radicals, measuring ferric ion reducing power (FRAP), and assessing the impact of the strains on the α-amylase enzyme. Additionally, the hydrophobicity potential, aggregation and coaggregation capacities, antibacterial activity, and absence of hemolytic activity were investigated. Ten (10) out of the fifty-four (54) strains exhibited characteristics of probiotics like resistance at a low gastric pH (2.0-3.0) (> 55% survival rate) and survival under different concentrations of NaCl and bile salts 0.3%-1% (> 80% survival rate). All the isolated strains exhibited high hydrophobicity potential, remarkable aggregation and coaggregation capacities, and antibacterial activity but no hemolytic activity. Because of the antioxidant capacity of the selected strains, every strain seems to be capable of efficiently scavenging DPPH and ABTS•+ radicals, superoxide dismutase and hydroxyl radical scavenging activity, and high resistance to H

Indexed as

Algerian ecosystemsAntidiabeticAntimicrobial activityAntioxidant activityLactic acid bacteriaProbiotic properties

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.