Evidence map›Paper›PMID 41307439›Full record

Trial reportJournal of viral hepatitis2026

Pharmacist-Led Hepatitis C Diagnosis and Rapid Management-In Community (PHARM-C): Results From a Phase IV Nonblinded Randomised Controlled Trial.

Mia J Biondi, Camelia I Capraru, Ben Harper, Preeti Gill, Cheryl H Dale, Jennifer Nicolle, Dixon Chung, Matthew Boutrous, Alexandra D Wilson, Vincent Lam and 8 more

Abstract readRandomized Controlled TrialClinical Trial, Phase IV
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of viral hepatitis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Mia J BiondiSchool of Nursing, York University, Toronto, Ontario, Canada.ORCID 0000-0002-1409-9908
Camelia I CapraruViral Hepatitis Care Network (VIRCAN), Toronto Centre for Liver Disease, Toronto, Ontario, Canada.
Ben HarperSpecialtyRx Solutions, Toronto, Ontario, Canada.
Preeti GillSpecialtyRx Solutions, Toronto, Ontario, Canada.
Cheryl H DaleViral Hepatitis Care Network (VIRCAN), Toronto Centre for Liver Disease, Toronto, Ontario, Canada.
Jennifer NicolleCoderix Medical Clinic, Toronto, Ontario, Canada.
Dixon ChungWoodgreen Pharmacy, Toronto, Ontario, Canada.
Matthew BoutrousWoodgreen Pharmacy, Toronto, Ontario, Canada.
Alexandra D WilsonCoderix Medical Clinic, Toronto, Ontario, Canada.
Vincent LamCoderix Medical Clinic, Toronto, Ontario, Canada.
David MorkosWoodgreen Pharmacy, Toronto, Ontario, Canada.
Bethany BarberViral Hepatitis Care Network (VIRCAN), Toronto Centre for Liver Disease, Toronto, Ontario, Canada.
Mediongo-Abasi UsoroViral Hepatitis Care Network (VIRCAN), Toronto Centre for Liver Disease, Toronto, Ontario, Canada.
Andrew B MendlowitzViral Hepatitis Care Network (VIRCAN), Toronto Centre for Liver Disease, Toronto, Ontario, Canada.
Hemant ShahViral Hepatitis Care Network (VIRCAN), Toronto Centre for Liver Disease, Toronto, Ontario, Canada.
Guillaume FontaineIngram School of Nursing, McGill University, Montreal, Quebec, Canada.ORCID 0000-0002-7806-814X
Bettina HansenViral Hepatitis Care Network (VIRCAN), Toronto Centre for Liver Disease, Toronto, Ontario, Canada.
Jordan J FeldViral Hepatitis Care Network (VIRCAN), Toronto Centre for Liver Disease, Toronto, Ontario, Canada.ORCID 0000-0003-2640-2211

Funding

AbbVie Canada
6 · The paper itself

Abstract

This was a nonblinded randomised controlled trial comparing pharmacist-led hepatitis C virus (HCV) treatment in the community, to tertiary care hepatology. Of 34 antibody-positive individuals, 28 completed a rapid HCV RNA test in the pharmacy. The study was terminated after randomising 11 participants over 15 months (recruitment continued until ~27 months), as a result of feasibility concerns of pharmacist-led care, and here we highlight important lessons learned to consider for future efforts.

Indexed as

Antiviral AgentsHepatitis CPharmacistsAdultAgedFemaleHepacivirusHumansMaleMiddle AgedRNA, ViralAntiviral AgentsRNA, Viraleliminationhepatitis C virusmodels of carepharmacist‐led treatmenttestingtreatment

Identifiers

PMID41307439
PMCPMC12659689

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.