Trial reportClinical nephrology2025
Impact of dietary counseling on Mediterranean diet principles on dietary fiber intake and serum uremic toxins in patients treated with peritoneal dialysis: A pilot study.
Trial report in Clinical nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Comment on the study: "Association of the newly proposed dietary index for gut microbiota and chronic kidney disease".International urology and nephrology · 2026Article
- Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe Mediterranean diet (MD) offers numerous health benefits, including improvements in cardiovascular health, cognitive function, and reduced inflammation. Its role in patients with chronic kidney disease (CKD), particularly those undergoing peritoneal dialysis (PD), remains understudied, but attractive. This study evaluated achieved adherence to the MD, impact on dietary fiber intake, and serum uremic toxins in PD patients. MATERIALS AND
methodsAn interventional randomized pilot study was conducted on 21 PD patients, randomized into intervention (MD diet counseling) and control groups (standard diet). Dietary intake, fiber consumption, serum potassium, phosphate and serum uremic toxins (trimethylamine-N-oxide (TMAO), p-cresyl sulfate (pCS), and indoxyl sulfate (IS)) were measured before and after a 4-week intervention. Dietary adherence was assessed using the Mediterranean Diet Adherence Screener (MEDAS). Statistical analyses compared the changes between groups.
resultsAdherence to the principles of MD significantly improved in the intervention group (MEDAS: 6.6 ± 1.0 to 8.8 ± 1.2, p < 0.001). Dietary fiber intake increased modestly but not significantly (16.7 ± 6.7 g/day to 19.8 ± 7.5 g/day, p = 0.374). Serum levels of uremic toxins showed no significant change, while potassium and phosphate levels remained stable.
conclusionThe MD counseling improved dietary adherence to the goals of MD without negatively affecting serum electrolyte and phosphate control in PD patients. No significant changes were observed in serum uremic toxin levels or dietary fiber intake.
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