Observational studyClinical nephrology2025
Eight-point lung ultrasonography protocol for assessing hypervolemia in chronic hemodialysis patients: A pilot study.
Observational study in Clinical nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
backgroundHypervolemia (HV) and arterial stiffness present an important problem for chronic hemodialysis (HD) patients. The most promising methods for evaluating excess fluid are bioelectrical impedance analysis (BIA) and lung ultrasonography with B-line assessment (LUS). The latter is traditionally performed in 28 anatomical locations on the front side of the chest. The study aimed to investigate whether a shorter LUS procedure in 8 locations correlates with other markers of HV and arterial stiffness. MATERIALS AND
methodsWe performed a single dialysis center observational study in adult chronic HD patients. Patients had to be without active malignancy, infection, chronic atrial fibrillation, carotid stenosis, severe aortic stenosis, or peripheral artery disease. We performed predialysis blood pressure measurements, LUS on 8 predefined locations, BIA, carotid-femoral pulse wave velocity (cfPWV) assessment, and laboratory values of the N-terminal prohormone of brain natriuretic peptide.
results19 patients were included, 7 male (36.8%). The median age of the patients was 71 years (IQR (60 - 74)), the median dialysis vintage was 51 months (IQR (27 - 87)). We found a statistically significant positive correlation between LUS and overhydration measured by BIA (r
conclusionLUS in 8 locations is associated with markers of HV in HD patients, correlating positively with BIA measurements. Its correlation with cfPWV should be further investigated.
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