Evidence map›Paper›PMID 41307408›Full record

ArticleStatistics in medicine2025

A Tutorial for Propensity Score Weighting Methods Under Violations of the Positivity Assumption.

Yi Liu, Yuan Wang, Ying Gao, Tonia Poteat, Roland A Matsouaka

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Article in Statistics in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yi LiuDepartment of Statistics, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0002-0935-007X
Yuan WangDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina, USA.
Ying GaoDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina, USA.
Tonia PoteatSchool of Nursing, Duke University, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0001-6541-3787
Roland A MatsouakaDuke Clinical Research Institute, Durham, North Carolina, USA.

Funding

Science CoreP2CHD065563 · NICHD · DUKE UNIVERSITY · PI Giovanna M Merli · 2015 to 2026
$5.7M
Integrated Biostatistical Training for CVD ResearchT32HL079896 · NHLBI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Sean M O'Brien, Ana-Maria Staicu · 2006 to 2026
$4.1M
NHLBI NIH HHS T32 HL079896NHLBI NIH HHS T32HL079896NICHD NIH HHS P2C HD065563
6 · The paper itself

Abstract

Violations of the positivity assumption can render conventional causal estimands unidentifiable, including the average treatment effect (ATE), the average treatment effect on the treated (ATT), and the average treatment effect on the controls (ATC). Shifting the inferential focus to their alternative counterparts-the weighted ATE (WATE), the weighted ATT (WATT), and the weighted ATC (WATC)-offers valuable insights into treatment effects while preserving internal validity. In this tutorial, we provide a comprehensive review of recent advances in propensity score (PS) weighting methods, along with practical guidance on how to select a primary target estimand (while other estimands serve as supplementary analyses), implement the corresponding PS-weighted estimators, and conduct post-weighting diagnostic assessments. The tutorial is accompanied by a user-friendly R package, ChiPS. We demonstrate the pertinence of various estimators through extensive simulation studies. We illustrate the flow of the tutorial on two real-world case studies: (i) Effect of smoking on blood lead level using data from the 2007-2008 National Health and Nutrition Examination Survey (NHANES); and (ii) Impact of history of sex work on HIV status among transgender women in South Africa.

Indexed as

Propensity ScoreComputer SimulationData Interpretation, StatisticalFemaleHumansModels, StatisticalNutrition SurveysSmokingcausal inferenceoverlap weightspositivitytarget populationunconfoundednessweighted average treatment effect

Identifiers

PMID41307408
PMCPMC12659692

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.