Evidence map›Paper›PMID 41307358›Full record

ArticleAnnals of clinical and translational neurology2026

Daratumumab Treatment for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): A Case Report.

Xueyu Zhang, Jianli Zhao, Xue Zhao, Xiaowei Hu, Zichun Xiao, Jie Wu, Xiaowen Li, Jing Xu, Yu-Jing Li

Abstract readCase Reports
In one paragraph

Article in Annals of clinical and translational neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xueyu ZhangDepartment of Neurology, Tianjin Medical University General Hospital, Tianjin, China.ORCID 0009-0002-4585-6315
Jianli ZhaoDepartment of Neurology, Tianjin Medical University General Hospital, Tianjin, China.
Xue ZhaoDepartment of Neurology, Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin, China.
Xiaowei HuDepartment of Neurology, Tianjin Medical University General Hospital, Tianjin, China.
Zichun XiaoDepartment of Neurology, Tianjin Medical University General Hospital, Tianjin, China.
Jie WuDepartment of Neurology, Tianjin Medical University General Hospital, Tianjin, China.
Xiaowen LiDepartment of Neurology, Tianjin Medical University General Hospital, Tianjin, China.
Jing XuDepartment of Neurology, Tianjin Medical University General Hospital, Tianjin, China.
Yu-Jing LiDepartment of Neurology, Tianjin Medical University General Hospital, Tianjin, China.ORCID 0009-0000-6778-7889

Funding

National Natural Science Foundation of China 81601002Natural Science Foundation of Tianjin Education Commission 2020KJ159
6 · The paper itself

Abstract

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune-mediated neuropathy featuring progressive weakness, sensory deficits, and areflexia. While corticosteroids, intravenous immunoglobulin, and plasmapheresis are effective first-line immunotherapies, a subset of patients remains treatment-refractory. Daratumumab, an anti-CD38 monoclonal antibody approved for multiple myeloma, demonstrates immunomodulatory effects suggesting utility in refractory neuroimmune disorders. However, evidence for its efficacy in CIDP remains limited. We report a case study of treatment-refractory CIDP successfully managed with daratumumab, including 1 year follow-up data.

Indexed as

Antibodies, MonoclonalImmunologic FactorsPolyradiculoneuropathy, Chronic Inflammatory DemyelinatingFemaleHumansMaleMiddle AgedAntibodies, MonoclonaldaratumumabImmunologic Factorsanti‐CD38 antibodyCIDPDaratumumabhumanized monoclonal antibodyneuroimmune diseases

Identifiers

PMID41307358
PMCPMC12968456

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.