Evidence map›Paper›PMID 41307250›Full record

ArticleNeural regeneration research2026

Hippocampal neural stem cell-derived extracellular vesicles modulate microglia to promote resilience against tau oligomers.

Salvatore Saieva, Pietro Scaduto, Anna Fracassi, Jutatip Guptarak, Wen-Ru Zhang, Kathia Johnson, Daniel C Jupiter, Michela Marcatti, Olga Zolochevska, Giulio Taglialatela and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neural regeneration research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Salvatore SaievaMitchell Center for Neurodegenerative Diseases, Department of Neurology, The University of Texas Medical Branch, Galveston, TX, USA.
Pietro ScadutoMitchell Center for Neurodegenerative Diseases, Department of Neurology, The University of Texas Medical Branch, Galveston, TX, USA.
Anna FracassiMitchell Center for Neurodegenerative Diseases, Department of Neurology, The University of Texas Medical Branch, Galveston, TX, USA.
Jutatip GuptarakMitchell Center for Neurodegenerative Diseases, Department of Neurology, The University of Texas Medical Branch, Galveston, TX, USA.
Wen-Ru ZhangMitchell Center for Neurodegenerative Diseases, Department of Neurology, The University of Texas Medical Branch, Galveston, TX, USA.
Kathia JohnsonDepartment of Anesthesiology, The University of Texas Medical Branch, Galveston, TX, USA.
Daniel C JupiterDepartment of Biostatistics & Data Science, Department of Orthopaedic Surgery and Rehabilitation, The University of Texas Medical Branch (UTMB), Galveston, TX, USA.
Michela MarcattiMitchell Center for Neurodegenerative Diseases, Department of Neurology, The University of Texas Medical Branch, Galveston, TX, USA.
Olga ZolochevskaMitchell Center for Neurodegenerative Diseases, Department of Neurology, The University of Texas Medical Branch, Galveston, TX, USA.
Giulio TaglialatelaMitchell Center for Neurodegenerative Diseases, Department of Neurology, The University of Texas Medical Branch, Galveston, TX, USA.ORCID 0000-0003-4795-447
Maria-Adelaide MicciDepartment of Anesthesiology, The University of Texas Medical Branch, Galveston, TX, USA.ORCID 0000-0001-6689-2994

Funding

Promoting Brain Resilience to Alzheimer's NeuropathologyR01AG069433 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI MICCI, MARIA-ADELAIDE, TAGLIALATELA, GIULIO · 2020 to 2024
$3.9M
NIA NIH HHS R01 AG069433
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer’s diseasehippocampusimmune responselysosomesmicroglianeural stem cellsneuroinflammationsingle-nuclei RNA sequencingsmall extracellular vesiclesTau oligomers

Identifiers

PMID41307250
PMCPMC13557526

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.