Evidence map›Paper›PMID 41307169›Full record

ArticleEmerging microbes & infections2026

Crimean-Congo hemorrhagic fever virus localization and shedding in the reproductive tract of lethal and survivor mouse models.

Teresa E Sorvillo, Jana M Ritter, Stephen R Welch, Katherine A Davies, JoAnn D Coleman-McCray, Heather M Hayes, Georgia Ficarra, Julu Bhatnagar, Scott D Pegan, Éric Bergeron and 3 more

Abstract read
In one paragraph

Article in Emerging microbes & infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Teresa E SorvilloCDC Foundation assigned to Viral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0003-2943-4040
Jana M RitterInfectious Diseases Pathology Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0002-4768-162X
Stephen R WelchViral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0002-6905-8521
Katherine A DaviesViral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0002-1643-7093
JoAnn D Coleman-McCrayViral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0003-0396-2224
Heather M HayesInfectious Diseases Pathology Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0009-0001-9553-1175
Georgia FicarraInfectious Diseases Pathology Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0002-1210-8516
Julu BhatnagarInfectious Diseases Pathology Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0002-4357-7833
Scott D PeganDivision of Biomedical Sciences, University of California Riverside, Riverside, CA, USA.ORCID 0000-0002-2958-5319
Éric BergeronViral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0003-3398-8628
Joel M MontgomeryViral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0003-0523-4431
Christina F SpiropoulouViral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0001-8406-3161
Jessica R SpenglerViral Special Pathogens Branch, Division of High-Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA.ORCID 0000-0002-5383-0513

Funding

Origin of the innate immunity suppression caused by nairovirus' protease activityR01AI151006 · NIAID · UNIVERSITY OF GEORGIA · PI PEGAN, SCOTT DUSAN · 2020 to 2024
$2.1M
Identification of GP38 and NP antibodies and their protective mechanisms against CCHFVR01AI187352 · NIAID · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Scott Dusan Pegan, Mohammad Mohseni Sajadi · 2025 to 2026
$1.4M
NIAID NIH HHS R01 AI151006NIAID NIH HHS R01 AI187352
6 · The paper itself

Abstract

Hemorrhagic fever viruses have been shown to localize to immune-privileged sites, including the reproductive tract, raising important questions about long-term persistence and the potential for sexual transmission. Anecdotal evidence of sexual transmission of Crimean-Congo hemorrhagic fever virus (CCHFV) has been reported, and

Indexed as

GenitaliaHemorrhagic Fever, CrimeanHemorrhagic Fever Virus, Crimean-CongoVirus SheddingAnimalsDisease Models, AnimalFemaleHumansMaleMiceRNA, ViralViral LoadRNA, ViralCrimean-Congo hemorrhagic fever virushemorrhagic fever virusmicereproductive tractsexual transmissionviral persistence

Identifiers

PMID41307169
PMCPMC12777786

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.