Evidence map›Paper›PMID 41307161›Full record

ReviewMass spectrometry reviews

Mass Spectrometry-Based Applications in Tannin Analytics: From Qualitative and Quantitative Analyses to Biological Activity.

Marica T Engström, Maarit Karonen

Abstract readReview
In one paragraph

Review in Mass spectrometry reviews. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. High-Performance Bio-Glue From the Berries of a Parasitic Plant.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  2. Enzyme-Assisted Ultrasonic Extraction of Flavonoids fromAntioxidants (Basel, Switzerland) · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marica T EngströmBioanalytical Laboratory, Institute of Biomedicine, University of Turku, Turku, Finland.ORCID 0000-0003-4123-6039
Maarit KaronenNatural Chemistry Research Group, Department of Chemistry, University of Turku, Turku, Finland.ORCID 0000-0002-9964-6527

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tannins are widespread specialized plant metabolites that contribute significantly to the polyphenol content of plant-based diets. Their effects on human and animal health vary depending on their structure, with potential benefits including antioxidative, antimicrobial, anthelmintic, and anticarcinogenic properties. Understanding tannin composition and quantity in plant products is essential, as their bioactivities are influenced by their functional groups. Mass spectrometry-based techniques excel in tannin analysis, offering both qualitative and quantitative insights. Combining ultrahigh-performance liquid chromatography with electrospray ionization and high-resolution and triple quadrupole mass analyzers is optimal for comprehensive tannin profiling. Such an approach enables precise analysis and helps predict tannin bioactivities. This review highlights the mass spectrometric analysis of proanthocyanidins and hydrolysable tannins, addressing ionization techniques, interpretation of multiply charged ions, characteristic fragmentations, and reaction monitoring. Applications related to tannin bioactivities are also briefly discussed, demonstrating the utility of mass spectrometry in tannin analysis in complex sample matrices.

Indexed as

Mass SpectrometryTanninsAnimalsAntioxidantsChromatography, High Pressure LiquidHumansHydrolyzable TanninsProanthocyanidinsSpectrometry, Mass, Electrospray IonizationAntioxidantsHydrolyzable TanninsProanthocyanidinsTanninsbioactivityelectrospray ionizationfragmentation patternshigh‐resolution mass spectrometrymultiple reaction monitoring

Identifiers

PMID41307161
PMCPMC12706721

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.