Evidence map›Paper›PMID 41307070›Full record

ReviewNeuropsychiatric disease and treatment2025

Improving Post-Stroke Cognitive Impairment via Cognitive and Motor Dual Task Gait Training: Potential Mechanisms and Clinical Value.

Jianping Cao, Peiyan Hu, Ling Li, Fangyu Dai, Ying Jin

Abstract readReview
In one paragraph

Review in Neuropsychiatric disease and treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jianping CaoDepartment of Rehabilitation Medicine, Zhoushan Hospital, Zhoushan, 316000, People's Republic of China.ORCID 0009-0009-0792-092X
Peiyan HuDepartment of Rehabilitation Medicine, Zhoushan Hospital, Zhoushan, 316000, People's Republic of China.
Ling LiDepartment of Neurology, Zhoushan Hospital, Zhoushan, 316000, People's Republic of China.
Fangyu DaiDepartment of Neurology, Zhoushan Hospital, Zhoushan, 316000, People's Republic of China.
Ying JinDepartment of Rehabilitation Medicine, The Second Affiliated Hospital, Zhejiang University, Hangzhou, 310052, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-stroke cognitive impairment (PSCI) severely impacts patients' quality of life and functional recovery, with its incidence rising alongside global population aging. Cognitive-walking dual-task training, which integrates cognitive and motor elements, has emerged as a key focus in rehabilitation research in recent years. This review summarizes its value and neural mechanisms in improving PSCI. By integrating randomized controlled trials and functional imaging studies, it assesses the training's effects on cognitive and motor functions and reveals the association between brain region activation and cognitive recovery. The training can enhance cognitive abilities such as attention and executive function, improve motor functions including gait and balance, and boost quality of life. It promotes neuroplasticity, strengthens activation and connectivity of key brain regions like the prefrontal cortex, and regulates Brain-derived neurotrophic factor (BDNF) expression. Technologies such as Functional Near-Infrared Spectroscopy (fNIRS) and Functional magnetic resonance imaging (fMRI) confirm its role in brain function remodeling, and it outperforms traditional training and aerobic exercise alone in enhancing dual-task performance. This training provides a basis for PSCI rehabilitation. Future research should optimize individualized protocols, verify long-term efficacy, and advance the application of multimodal imaging and intelligent platforms to refine rehabilitation strategies.

Indexed as

cognitive impairmentdual task trainingneural mechanismsstrokewalking rehabilitation

Identifiers

PMID41307070
PMCPMC12645990

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.