Evidence map›Paper›PMID 41306996›Full record

ArticleChemical science2026

Enantioselective copper-catalysed defluorinative alkylation of polyfluoroarenes with alkenes and 1,3-dienes.

Dazhen Shi, Lihan Zhu, Ying Jiang, Simin Wang, Jianjun Yin, Xiuping Yuan, Shucheng Ma, Xiaoyu Li, Jiaqiong Sun, Qian Zhang and 1 more

Abstract read
In one paragraph

Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dazhen ShiJilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University Changchun 130024 China xiongt626@nenu.edu.cn zhangq651@nenu.edu.cn.
Lihan ZhuJilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University Changchun 130024 China xiongt626@nenu.edu.cn zhangq651@nenu.edu.cn.ORCID https://orcid.org/0000-0002-1213-5717
Ying JiangJilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University Changchun 130024 China xiongt626@nenu.edu.cn zhangq651@nenu.edu.cn.
Simin WangJilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University Changchun 130024 China xiongt626@nenu.edu.cn zhangq651@nenu.edu.cn.
Jianjun YinJilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University Changchun 130024 China xiongt626@nenu.edu.cn zhangq651@nenu.edu.cn.
Xiuping YuanJilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University Changchun 130024 China xiongt626@nenu.edu.cn zhangq651@nenu.edu.cn.
Shucheng MaJilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University Changchun 130024 China xiongt626@nenu.edu.cn zhangq651@nenu.edu.cn.
Xiaoyu LiJilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University Changchun 130024 China xiongt626@nenu.edu.cn zhangq651@nenu.edu.cn.
Jiaqiong SunJilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University Changchun 130024 China xiongt626@nenu.edu.cn zhangq651@nenu.edu.cn.ORCID https://orcid.org/0000-0002-8724-2664
Qian ZhangJilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University Changchun 130024 China xiongt626@nenu.edu.cn zhangq651@nenu.edu.cn.ORCID https://orcid.org/0000-0002-3136-841X
Tao XiongJilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University Changchun 130024 China xiongt626@nenu.edu.cn zhangq651@nenu.edu.cn.ORCID https://orcid.org/0000-0002-2516-084X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite impressive advances in the field of defluorinative alkylation of polyfluoroarenes, the corresponding asymmetric counterpart has remained a formidable challenge. Herein, we present the first example of asymmetric defluorinative alkylation of polyfluoroarenes with readily accessible alkenes, 1,3-dienes, and even (

Identifiers

PMID41306996
PMCPMC12645699

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.