ReviewFrontiers in immunology2025
Phytochemicals as modulators of dendritic cell functions: implications for tolerogenic cell-based therapy.
Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Therapeutic Potential of Ginger Rhizomes (Zingiber officinale) on Leukemia.Biotechnology and applied biochemistry · 2026Review
- Resveratrol Nanoformulations for Cancer Management: A Comprehensive Review of Disease-Specific Strategies and Clinical Translational Barriers.International journal of nanomedicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dendritic cells (DCs) constitute a heterogeneous population of immune cells that acting as antigen presenting cells link innate and adaptive immune responses. Their functions are mainly dictated by microenvironmental cues, enabling them to either maintain immune tolerance or initiate robust humoral and cellular immune responses. While DCs are important for orchestrating immune responses, accumulating evidence suggests that aberrant DC activation contributes to the pathogenesis of autoimmune and chronic inflammatory diseases, making them promising targets for therapeutic modulation. Modulating DC functionality therefore represents a potent strategy to attenuate excessive inflammation in such conditions. Plant-derived bioactive compounds, or phytochemicals, are structurally diverse secondary metabolites with established anti-inflammatory and immunomodulatory properties. This review consolidates current
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.