Evidence map›Paper›PMID 41306959›Full record

ArticleFrontiers in immunology2025

Systemic inflammation impairs recovery from hookworm-associated anemia in a wild marine mammal host.

Violetta Zaitseva, Nanami Arakawa, Carmon Co, Aranza Gomez-Camus, Diego Perez-Venegas, Felipe Montalva, Josefina Gutiérrez, Claudia Ulloa-Contreras, Ricardo Chihuailaf, Claudio Verdugo and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Violetta ZaitsevaDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
Nanami ArakawaDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
Carmon CoDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
Aranza Gomez-CamusDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
Diego Perez-VenegasFacultad de Ciencias de la Vida, Universidad Andrés Bello, Santiago, Chile.
Felipe MontalvaGuafo Science Research Group, Punta Weather, Isla Guafo s/n, Quellón, Región de los Lagos, Chile.
Josefina GutiérrezGuafo Science Research Group, Punta Weather, Isla Guafo s/n, Quellón, Región de los Lagos, Chile.
Claudia Ulloa-ContrerasMillennium Institute Biodiversity of Antarctic and Subantarctic Ecosystems (BASE), Santiago, Chile.
Ricardo ChihuailafInstituto de Ciencias Clínicas Veterinarias, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia, Chile.
Claudio VerdugoInstituto de Patología Animal, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia, Chile.
Dorothee BienzleDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
Mauricio SeguelDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation is a critical defense against pathogens but can impair iron metabolism and erythropoiesis, potentially causing or exacerbating anemia during infection. However, the ecological and evolutionary relevance of this trade-off remains poorly understood. Naturally co-evolved host-parasite systems offer a unique opportunity to explore how inflammatory responses balance the benefits of pathogen control against potential physiological costs. We examined how systemic inflammation affects recovery from hookworm-associated anemia in South American fur seal (

Indexed as

AncylostomatoideaAnemiaHookworm InfectionsInflammationAnimalsChileCytokinesFemaleHost-Parasite InteractionsIronMaleCytokinesIronhelminthhookwormIL-10IL-6ironneutrophilotariiduncinaria

Identifiers

PMID41306959
PMCPMC12643882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.