Trial reportDrug design, development and therapy2025
Effect of Fascia Iliaca Compartment Block with Liposomal Bupivacaine on the Quality of Recovery After Hip Fracture Surgery: A Prospective, Randomized, Controlled Clinical Study.
Trial report in Drug design, development and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07643792 (Fascia Iliaca Block Using Liposomal Bupivacaine for Analgesia After Hip Surgery), which is not on this map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Fascia Iliaca Block Using Liposomal Bupivacaine for Analgesia After Hip Surgery: a Randomized Trial
Who cites it
2 citing papers in PubMed.
- Median effective concentration of liposomal bupivacaine for ultrasound-guided supra-inguinal fascia iliaca compartment block in older adults undergoing total hip arthroplasty: a dixon geometric up-and-down dose-finding study.BMC anesthesiology · 2026Trial
- Anterior Quadratus Lumborum Block with Liposomal Bupivacaine versus Ropivacaine for Postoperative Recovery in Laparoscopic Colorectal Surgery: A Randomized Controlled Trial.Drug design, development and therapy · 2026Trial
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To investigate the effect of a fascia iliaca compartment block with liposomal bupivacaine on the quality of recovery after hip fracture surgery. Patients and Methods: Seventy patients who underwent hip fracture surgery were randomized 1:1 to either the liposomal bupivacaine group (LB group) or ropivacaine group (R group). The LB and R groups received 0.333% liposomal bupivacaine and 0.375% ropivacaine, respectively, for fascia iliaca compartment block. The Quality of Recovery-15 (QoR-15) was assessed at 72 hours postoperatively. We performed between-group comparisons of the highest Numerical Rating Scale (NRS) score during activities at 0-24 hours, 24-48 hours and 48-72 hours postoperatively, amount of opioid consumption within 72 hours postoperatively, recovery time for muscle strength grades II and III, postoperative time to first mobilization, postoperative length of hospital stay, incidence of postoperative adverse reactions, and scores for patient satisfaction with pain relief. Results: Compared to the R group, the LB group had significantly higher QoR-15 scores and lower opioid consumption at 72 hours postoperatively. There was no significant between-group difference in the highest NRS score during activity within 24 hours postoperatively. However, the LB group had lower NRS scores than the R group within the 24-48 and 48-72 hours postoperatively. The postoperative time to first mobilization was significantly shorter in the LB group than in the R group. However, there were no significant between-group differences in the recovery time for grade III muscle strength, postoperative length of hospital stay, incidence of adverse reactions, and pain satisfaction scores. Conclusion: Fascia iliaca compartment block with liposomal bupivacaine can significantly improve the quality of postoperative recovery and reduce opioid consumption in patients undergoing hip fracture surgery.
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