Evidence map›Paper›PMID 41306764›Full record

ReviewFrontiers in allergy2025

Spices, herbs and allergic reactions in children: myth or reality - a narrative review with scoping elements.

Elena Camelia Berghea, Gavriela Feketea, Maria-Teodora Cosoreanu, Olivia-Mihaela Popa, Marcela Daniela Ionescu, Corina Porr, Florian Berghea, Emilia Vassilopoulou

Abstract readReview
In one paragraph

Review in Frontiers in allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elena Camelia BergheaDepartment of Pediatrics, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Gavriela FeketeaPediatric Allergy Outpatient Clinic, Pediatric Department, Karamandaneio Children's Hospital of Patra, Patra, Greece.
Maria-Teodora CosoreanuDepartment of Pediatrics, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Olivia-Mihaela PopaDepartment of Pathophysiology and Immunology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Marcela Daniela IonescuDepartment of Pediatrics, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Corina PorrFaculty of Medicine, Lucian Blaga University of Sibiu, Sibiu, Romania.
Florian BergheaCarol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Emilia VassilopoulouDepartment of Nutritional Sciences and Dietetics, School of Health Sciences, International Hellenic University, Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spices and herbs are widely used for their flavor and therapeutic properties. This narrative review explores current evidence on spice and herb allergies in children, using a scoping approach to synthesize data from case reports, clinical, immunologic, molecular studies, regulatory sources, and previous reviews. Selected adult cases were included for context. Spice and herb allergies are increasingly recognized in children, with symptoms ranging from mild oral reactions to anaphylaxis. The most frequently implicated spices include mustard, celery, coriander, fennel, cumin, anise, pepper, and herbs from the Lamiaceae-family such as mint, oregano, and sage. Both IgE- and non-IgE-mediated mechanisms are involved, with cross-reactivity to pollens (birch and mugwort) being common. Diagnosis remains challenging due to limited standardized tests; oral food challenge is the gold standard. Management relies on strict allergen avoidance and emergency preparedness. Improved clinical awareness, diagnostic tools, and clearer labeling-especially regarding hidden allergens-are crucial for effective care.

Indexed as

allergic reactionsallergyherbmustard allergyspices

Identifiers

PMID41306764
PMCPMC12644062

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.