ReviewInternational journal of reproductive biomedicine2025
The evaluation role of T helper 17 cells in pregnancy and abortion: A molecular and future perspective: Narrative review.
Review in International journal of reproductive biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- The Role of Immunologic Factors in Endometrial Receptivity: An Embryo-Endometrium Dialogue.International journal of molecular sciences · 2026Review
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5 authors.
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Abstract
T helper (Th)17 is one of the immune cells playing a vital role in cellular processes, especially abortion. This cell regulates many cells and mediators of the immune system through genes and molecular pathways. This research evaluates the function of Th17 in pregnancy and abortion. This immune system cell normally regulates the activity of immune cells and inflammatory responses. Th17 cells affect decidua, placental formation, and trophoblast invasion in pathogenic conditions. Th17 acts mainly through secreting interleukin (IL-17). This cell disrupts molecular pathways and progesterone secretion through molecular pathways and genes. Besides, it was shown that the level of IL-17 is constantly enhanced within the gestation time of healthy pregnant women. Through the integration and summary of the literature, we conclude that a successful pregnancy requires a balanced Th17 cell response. However, since the exact mechanisms of Th17 cells during pregnancy remain unclear, further investigation is required to clarify this issue. In addition, the relationship between IL-17 and pregnancy complications is complex and requires further investigation. In this respect, the maternal immune reaction participates in keeping the balance of the Th17 immune response.
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