Evidence map›Paper›PMID 41306676›Full record

ArticleRSC advances2025

Riboflavin-sensitized photoinduced degradation of donepezil hydrochloride: kinetic and computational insights for pharmaceutical formulation.

Tooba Khan, Zubair Anwar, Reem Altaf, Ayesha Awan, Aisha Noreen, Muneeba Usmani, Muhammad Ahsan Ejaz, Anam Khan, Sofia Ahmed, Muhammad Ali Sheraz and 1 more

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tooba KhanDepartment of Pharmaceutical Chemistry, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University Gadap Road, Superhighway Karachi-75340 Pakistan zubair_ana@hotmail.com zubair_ana@baqai.edu.pk.
Zubair AnwarDepartment of Pharmaceutical Chemistry, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University Gadap Road, Superhighway Karachi-75340 Pakistan zubair_ana@hotmail.com zubair_ana@baqai.edu.pk.ORCID https://orcid.org/0000-0003-3822-7588
Reem AltafDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Capital University of Science and Technology Islamabad Expressway, Kahuta Road, Zone-V Islamabad Pakistan reem@cust.edu.pk.
Ayesha AwanDepartment of Pharmacognosy, Faculty of Pharmaceutical Sciences, Riphah International University G-7/4, 7th Avenue Islamabad Pakistan.
Aisha NoreenDepartment of Pharmaceutical Chemistry, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University Gadap Road, Superhighway Karachi-75340 Pakistan zubair_ana@hotmail.com zubair_ana@baqai.edu.pk.
Muneeba UsmaniDepartment of Pharmaceutics, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University Gadap Road, Superhighway Karachi-75340 Pakistan.
Muhammad Ahsan EjazDepartment of Pharmaceutical Chemistry, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University Gadap Road, Superhighway Karachi-75340 Pakistan zubair_ana@hotmail.com zubair_ana@baqai.edu.pk.
Anam KhanDepartment of Pharmaceutics, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University Gadap Road, Superhighway Karachi-75340 Pakistan.
Sofia AhmedDepartment of Pharmaceutics, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University Gadap Road, Superhighway Karachi-75340 Pakistan.ORCID https://orcid.org/0000-0002-0731-1237
Muhammad Ali SherazDepartment of Pharmaceutics, Baqai Institute of Pharmaceutical Sciences, Baqai Medical University Gadap Road, Superhighway Karachi-75340 Pakistan.ORCID https://orcid.org/0000-0002-6333-8178
Toufeeque AliLiaquat University Hospital Jamshoro Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Donepezil (DPZ) photosensitized degradation by riboflavin (RF) at pH 2.0-12.0 has been carried out in aerobic and anaerobic conditions under UV and visible irradiation to give an idea to pharmaceutical formulators to develop a stable co-formulation to administer to elderly patients with neurodegenerative diseases (Alzheimer's disease, Parkinson's disease). The photolysis rate constants (

Identifiers

PMID41306676
PMCPMC12645192

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.