Evidence map›Paper›PMID 41306672›Full record

ArticleFrontiers in nutrition2025

Changes in bile acid profiles and short-term weight loss in response to a low-calorie diet: a pilot study.

Ming-Xia Jiang, Chen-Jie Ling, Si-Cheng Qian, Jing-Nan Zhai, Jin-Yuan Huang, Ke-Ke Su, Xiang-Wei Wu, Qing-Zhen Han, Lin Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ming-Xia Jiang *Department of Clinical Nutrition, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Chen-Jie Ling *Department of Clinical Nutrition, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Si-Cheng QianClinical Testing Center, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Jing-Nan ZhaiDepartment of Clinical Nutrition, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Jin-Yuan HuangDepartment of Clinical Nutrition, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Ke-Ke SuDepartment of Clinical Nutrition, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Xiang-Wei WuClinical Testing Center, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Qing-Zhen HanClinical Testing Center, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.
Lin WangClinical Testing Center, The Fourth Affiliated Hospital of Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dietary intervention-induced modulation of bile acids may enhance metabolic homeostasis and facilitate weight reduction. We aimed to elucidate the role of bile acids and their association with the gut microbiota during weight reduction induced by a low-calorie diet (LCD). Methods: Twelve participants were enrolled, and body composition, serum bile acid profiles, and gut microbiota were analyzed at baseline and after a 4-week LCD intervention. Results: The LCD significantly reduced body weight (3.39 ± 1.99 kg, Conclusion: These findings suggest that increased LCA is associated with metabolic improvements during LCD intervention.

Indexed as

bile acidsgut microbiotalow-calorie dietobesityweight loss

Identifiers

PMID41306672
PMCPMC12643879

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.