ReviewFrontiers in nutrition2025
The impact of nutritional support therapy combined with conventional treatment models on short-term symptom improvement and complications in stroke patients: a systematic review and meta-analysis.
Review in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- GNRI-stratified enteral nutrition protocol for elderly mechanically ventilated ICU patients: development and preliminary application.Frontiers in nutrition · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To methodically assess the effectiveness of nutritional support therapy combined with conventional treatment on short-term symptom improvement, nutritional and immune recovery, and complication rates in stroke patients. Methods: A thorough literature search was carried out utilizing PubMed, EMBASE, ScienceDirect, the Cochrane Library, and major Chinese databases (CNKI, VIP, Wanfang, and CBM) from inception to the present. Randomized controlled trials (RCTs) evaluating the impact of nutritional support in stroke patients were included. Two reviewers independently extracted the data, and the Cochrane Handbook 5.3 was used to determine the risk of bias. RevMan 5.3 was used to conduct the meta-analysis. Results: Following PRISMA guidelines, 1,693 records were retrieved and screened, resulting in the inclusion of 8 randomized controlled trials with a total of 727 individuals. Meta-analysis revealed that nutritional support significantly improved Glasgow Coma Scale (GCS) scores, serum markers of nutritional status (Hb, TLC), and immune parameters (IgA, IgG, IgM). Pro-inflammatory cytokines (IL-2, IL-6, TNF- Conclusion: Nutritional support combined with conventional therapy improves nutritional and immune recovery and reduces infection risk in stroke patients. However, given the high heterogeneity and methodological limitations of included trials, the certainty of evidence remains low to very low, and these results should be interpreted cautiously.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.