SynthesisFrontiers in neurology2025
The efficacy and safety of acupuncture treatment for peripheral facial paralysis: an overview of systematic review and meta-analysis.
Synthesis in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Time to Complete Clinical Recovery and Its Predictors in Bell's Palsy Patients Receiving Acupuncture: A Prospective Cohort Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Warm acupuncture combined with precise meridian sinew needling for refractory peripheral facial paralysis: a propensity score-matched retrospective study on clinical efficacy and infrared thermal imaging.Frontiers in medicine · 2026Article
- Does acute-phase acupuncture at Hegu (LI04) promote facial nerve regeneration and upregulation of the PI3K/Akt/mTOR pathway? A hypothesis-generating study in a rabbit crush injury model.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Many studies have investigated the efficacy and safety of acupuncture in the treatment of peripheral facial palsy (PFP), but the results have been inconsistent. This study aimed to evaluate systematic reviews (SRs) and meta-analyses (MAs) of the treatment of PFP by integrating acupuncture, providing a basis for clinical treatment. Methods: We searched Wanfang, VIP, CNKI, CBM, Web of Science, PubMed, and Cochrane Library databases for SRs and MAs related to acupuncture treatment for PFP, from the establishment of the databases to May 1, 2025. We evaluated the methodology, reporting quality, and evidence quality of the included studies using the AMSTAR2, PRISMA, and GRADE tools. Results: This study included a total of 17 SRs and MAs. The AMSTAR2 assessment results showed that three studies were rated as having low methodological quality, while 14 studies were considered to have very low methodological quality. The PRISMA results indicated that two studies were of high quality, nine were of moderate quality, and six were of low quality. GRADE results indicated that only two items provided moderate-quality evidence, 22 items provided low-quality evidence, and 13 items provided very low-quality evidence. Acupuncture can improve the clinical efficacy of PFP, reduce recovery time, and has few adverse reactions. Conclusion: Acupuncture is effective in treating PFP, but methodological shortcomings in existing studies have resulted in limited evidence. In the future, it is necessary to follow the principles of evidence-based medicine to improve the quality of relevant RCTs and SRs and MAs studies and enhance the credibility of the evidence. Systematic review registration: PROSPERO, identifier: CRD420251033106.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.