ArticleFrontiers in neurology2025
Impact of low-level laser therapy on orthodontic pain.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Pain is a primary deterrent to patient compliance in orthodontics. While pharmacological options exist, their systemic side effects warrant exploration of non-invasive alternatives. This study introduces Low-Level Laser Therapy (LLLT) as a localized, non-pharmacological intervention and evaluates its efficacy in mitigating pain during the critical initial phase of fixed appliance treatment. Methods: In this prospective controlled study, 60 patients (aged 14.6-37.1 years) were randomized into an LLLT group ( Results: LLLT significantly reduced pain perception. Pain peaked on day 2 for both groups, but the VAS score was lower in the LLLT group (4.35) than the control group (5.30). By day 4, the difference was highly significant (LLLT: 2.05 vs. Control:3.77; Conclusion and application: LLLT is an effective and safe modality for reducing acute orthodontic pain. Its localized action, absence of systemic side effects, and positive influence on oral hygiene make it available clinical tool for improving patient comfort and compliance during orthodontic therapy. This study provides strong evidence supporting the integration of LLLT into routine orthodontic practice.
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