Evidence map›Paper›PMID 41306555›Full record

ArticleMedComm2025

Variations in Estimated Glomerular Filtration Rate Across Countries in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease and Their Association With Liver Fibrosis: A Multicenter Study.

Jing Zhao, Ferenc E Mózes, Xin-Yu Xu, Dong Ji, Huiqing Liang, Xiaoling Chi, Jinjun Chen, Takeshi Okanoue, Toshihide Shima, Yongfen Zhu and 44 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedComm, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

54 authors.

Jing ZhaoUrologic Nephrology Center Jiangnan University Medical Center Wuxi China.
Ferenc E MózesOxford Centre for Clinical Magnetic Resonance Research Division of Cardiovascular Medicine Radcliffe Department of Medicine University of Oxford Oxford UK.
Xin-Yu XuUrologic Nephrology Center Jiangnan University Medical Center Wuxi China.
Dong JiSenior Department of Hepatology The Fifth Medical Center of Chinese PLA General Hospital Beijing China.
Huiqing LiangHepatology Unit Xiamen Hospital of Traditional Chinese Medicine Xiamen Fujian China.
Xiaoling ChiDepartment of Hepatology The Second Affiliated Hospital of Guangzhou University of Chinese Medicine Guangdong Provincial Hospital of Chinese Medicine Guangzhou China.
Jinjun ChenHepatology Unit Department of Infectious Diseases Nanfang Hospital Southern Medical University Guangzhou China.
Takeshi OkanoueDepartment of Gastroenterology and Hepatology Saiseikai Suita Hospital Suita Japan.
Toshihide ShimaDepartment of Gastroenterology and Hepatology Saiseikai Suita Hospital Suita Japan.
Yongfen ZhuDepartment of Hepatology and Infection Sir Run Run Shaw Hospital Affiliated With School of Medicine Zhejiang University Hangzhou China.
Christian LabenzDepartment of Internal Medicine I University Medical Centre of the Johannes Gutenberg-University Mainz Mainz Rhineland-Palatinate Germany.ORCID https://orcid.org/0000-0001-8390-9663
Bihui ZhongDepartment of Gastroenterology the First Affiliated Hospital Sun Yat-sen University Guangzhou China.
Masato YonedaDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine Yokohama Japan.
Atsushi NakajimaDepartment of Gastroenterology and Hepatology Yokohama City University School of Medicine Yokohama Japan.
Junping ShiDepartment of Hepatology The Affiliated Hospital of Hangzhou Normal University Hangzhou China.
Jing ZhangThe Third Unit Department of Hepatology Beijing Youan Hospital Capital Medical University Beijing China.
Sanjiv MahadevaGastroenterology and Hepatology Unit Department of Medicine Faculty of Medicine University of Malaya Kuala Lumpur Malaysia.
Wah-Kheong ChanGastroenterology and Hepatology Unit Department of Medicine Faculty of Medicine University of Malaya Kuala Lumpur Malaysia.
Fangping HeDepartment of Hepatobiliary Pancreatic Surgery Eighth Hospital Affiliated to Sun Yat-Sen University Shenzhen Guangdong Province China.
Chun-Yan YeInstitute For the Study of Liver Diseases The Third People's Hospital of Changzhou Changzhou Jiangsu Province China.
Su LinDepartment of Hepatology Hepatology Research Institute The First Affiliated Hospital of Fujian Medical University Fuzhou China.
Adèle DelamarreCentre D'investigation De La Fibrose Hépatique Hôpital Haut-Lévêque Bordeaux University Hospital Pessac France.
Victor de LédinghenCentre D'investigation De La Fibrose Hépatique Hôpital Haut-Lévêque Bordeaux University Hospital Pessac France.
Monica Lupsor-PlatonDepartment of Medical Imaging "Prof. Dr. Octavian Fodor" Regional Institute of Gastroenterology and Hepatology ''Iuliu Hațieganu" University of Medicine and Pharmacy Cluj-Napoca Romania.
Zhonghua LuClinical Laboratory Center The Fifth People's Hospital of Wuxi Wuxi Jiangsu China.
Hong TangCenter of Infectious Diseases West China Hospital Sichuan University Chengdu China.
Jidong JiaLiver Research Center Beijing Friendship Hospital Capital Medical University Beijing China.
Peter J EddowesNational Institute for Health Research Nottingham Biomedical Research Centre Nottingham University Hospitals NHS Trust and University of Nottingham Nottingham UK.
Liang XuDepartment of Hepatology Tianjin Second People's Hospital Tianjin China.
Yiling LiDepartment of Gastroenterology First Affiliated Hospital of China Medical University Shenyang China.
Yuemin NanDepartment of Traditional and Western Medical Hepatology The Third Hospital of Hebei Medical University Shijiazhuang China.
Hong DengDepartment of Infectious Diseases The Third Affiliated Hospital of Sun Yat-Sen University Guangzhou China.
Junqi NiuDepartment of Hepatology Center of Infectious Diseases and Pathogen Biology The First Hospital of Jilin University Changchun China.
Xuebing YanDepartment of Infectious Disease The Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu China.
Qing YeDepartment of Hepatology of The Third Central Hospital of Tianjin Tianjin China.
Qinglei ZengDepartment of Infectious Diseases The First Affiliated Hospital of Zhengzhou University Zhengzhou China.
Yongjian ZhouDepartment of Gastroenterology and Hepatology Guangzhou First People's Hospital School of Medicine South China University of Technology Guangzhou China.
Jeremy F L CobboldTranslational Gastroenterology Unit University of Oxford Oxford UK.
Chenghai LiuInstitute of Liver Diseases Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Shanghai China.
Jie LiDepartment of Infectious Disease Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School Nanjing Jiangsu China.
Lei LiDepartment of Infectious Diseases The First Affiliated Hospital of Anhui Medical University Hefei China.
Jing WangDepartment of Hepatobiliary Diseases Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University Chengdu Sichuan Province China.
Fanpu JiDepartment of Infectious Diseases The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an China.
Jin ChaiDepartment of Gastroenterology Southwest Hospital Army Medical University Chongqing China.
Yongning XinDepartment of Infectious Diseases Qingdao Municipal Hospital Affiliated to Qingdao University Qingdao China.
Giovanni TargherDepartment of Medicine University of Verona Verona Italy.
Christopher D ByrneSouthampton National Institute For Health and Care Research Biomedical Research Centre University Hospital Southampton and University of Southampton Southampton General Hospital Southampton UK.
Yuchen FanDepartment of Hepatology Qilu Hospital of Shandong University Jinan China.
Jia-Hui ZhangDepartment of Paediatrics The Affiliated Wuxi Children's Hospital of Jiangnan University Wuxi Jiangsu China.
Geraldine OoiCentre For Obesity Research and Education Department of Surgery Monash University Melbourne Australia.
Jacob GeorgeStorr Liver Centre Westmead Institute for Medical Research Westmead Hospital and University of Sydney Sydney NSW Australia.
Michael PavlidesOxford Centre for Clinical Magnetic Resonance Research Radcliffe Department of Medicine and Oxford NIHR Biomedical Research Centre University of Oxford Oxford UK.
Dan-Qin SunUrologic Nephrology Center Jiangnan University Medical Center Wuxi China.
Ming-Hua ZhengMAFLD Research Center Department of Hepatology the First Affiliated Hospital of Wenzhou Medical University Wenzhou China.ORCID https://orcid.org/0000-0003-4984-2631

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) has become the most prevalent chronic liver disease globally. Previous studies have shown that MASLD is an independent risk factor for chronic kidney disease (CKD), but the variations in estimated glomerular filtration rate (eGFR) levels across countries with different ethnic backgrounds have not been extensively reported. We enrolled 3308 participants with biopsy-proven MASLD from 34 centers in this multinational study and analyzed the associations between eGFR and histological severity of liver fibrosis in different countries. European participants had lower eGFR levels (92.2 ± 20.7 vs. 104.7 ± 17.3 mL/min/1.73 m

Indexed as

epidemiologyestimated glomerular filtration rateliver fibrosismetabolic dysfunction‐associated fatty liver diseasemetabolic dysfunction‐associated steatotic liver disease

Identifiers

PMID41306555
PMCPMC12644250

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.