ArticleFrontiers in pediatrics2025
OCTA-based evaluation of the correlation between macular retinal and choroidal structural characteristics and refractive status in patients with retinopathy of prematurity.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: To investigate the correlation between macular retinal and choroidal structural characteristics and refractive status in preschool-aged children with retinopathy of prematurity (ROP), based on optical coherence tomography angiography (OCTA), and to analyze the relationship between serum vascular endothelial growth factor (VEGF) levels and microcirculatory alterations. Methods: 310 preterm children with a history of ROP who were followed up at our hospital between January 2022 and June 2024 were included. According to the International Classification of Retinopathy of Prematurity (ICROP), participants were categorized into mild ( Results: The myopia rate in the severe group (80.0%) was higher than that in the moderate (52.0%) and mild (18.7%) groups ( Conclusion: Increased FAZ area, decreased SCP vessel density, and decreased choroidal thickness were associated with the development of myopia. Serum VEGF levels were correlated with macular microcirculatory parameters.
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