SynthesisFrontiers in oncology2025
Association of preoperative controlling nutritional status score with clinical outcomes among surgical patients with esophageal cancer: a meta-analysis.
Synthesis in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The aim of this study was to identify the relationship between preoperative controlling nutritional status (CONUT) score and long-term and short-term outcomes in patients with esophageal cancer receiving esophagectomy. Methods: The Web of Science, EMBASE, PubMed, and CNKI databases were searched up to 24 January 2025. Primary outcome was long-term survival such as the overall survival (OS), disease-free survival (DFS), and cancer-specific survival (CSS). Secondary outcomes included the postoperative overall complication, incision infection, anastomotic fistula, pneumonia, respiratory complication, 90-day death, cardiovascular complication, major adverse cerebrocardiovascular event (MACCE), pulmonary atelectasis, and pulmonary embolism. Hazard ratio (HR) and odds ratio (OR) with 95% confidence interval (CI) were separately combined for the primary and secondary outcomes. Subgroup analysis for the OS and DFS by neoadjuvant therapy and pathological type was further conducted. Results: Eighteen studies with 5,495 cases were included. Pooled results manifested that elevated preoperative CONUT score predicted significantly worse OS (HR = 1.75, 95% CI: 1.30-2.37, Conclusion: Preoperative CONUT score might serve as a prognostic indicator in surgical esophageal cancer, and patients with elevated CONUT score are suggested to experience worse long-term and short-term clinical outcomes.
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