Evidence map›Paper›PMID 41306509›Full record

ArticleFrontiers in medicine2025

Case Report: Management of a pregnancy complicated by a symptomatic macroprolactinoma.

Spyridon Topis, Kalliopi Christodoulaki, Maria Riga, Ioannis Arkoulis, Theodoros Karampitsakos, Tatiana Sidiropoulou, Peter Drakakis, Anastasios Potiris, Sofoklis Stavros

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PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Spyridon TopisThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Kalliopi ChristodoulakiSecond Department of Anesthesiology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Maria RigaSecond Department of Anesthesiology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Ioannis ArkoulisThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Theodoros KarampitsakosThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Tatiana SidiropoulouSecond Department of Anesthesiology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Peter DrakakisThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Anastasios PotirisThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Sofoklis StavrosThird Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prolactinomas are the most common functional pituitary adenomas and may lead to infertility, visual field defects, and neurological impairment. Pregnancy poses unique challenges to women with macroprolactinomas due to the potential for tumor enlargement under the influence of gestational hormonal changes. Case: We present the case of a 40-year-old woman who conceived through Outcome: Delivery was uneventful, with no perioperative neurological or anesthetic complications. The patient was discharged in good general condition and commenced long-term dopamine agonist therapy, with planned close endocrinological and neurosurgical follow-up. Conclusion: This case highlights the importance of early diagnosis, individualized management, and multidisciplinary coordination in pregnant women with macroprolactinomas. Dopamine agonists remain the cornerstone of therapy and are generally safe during early pregnancy. Meticulous anesthetic planning is essential to optimize maternal and fetal outcomes.

Indexed as

cabergolinediplopiadopamine agonistsmacroprolactinomapituitary adenomapregnancyprolactinoma

Identifiers

PMID41306509
PMCPMC12644042

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