Evidence map›Paper›PMID 41306470›Full record

ArticleThe American journal of geriatric psychiatry. Open science, education, and practice2025

Relation Between Executive Function Test Performance and Treatment Outcomes During Brief Psychotherapies for Later-Life Depression.

Matthew S Schurr, Yiqun T Chen, Patrick J Raue, Patricia A Areán, George S Alexopoulos, Brenna N Renn

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of geriatric psychiatry. Open science, education, and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matthew S SchurrDepartment of Psychology (MSS, BNR), University of Nevada, Las Vegas, NV; Department of Psychiatry (MSS), McLean Hospital, Belmont, MA; Data Science Institute and Department of Biomedical Data Science (YTC), Stanford University, Stanford, CA; Department of Psychiatry and Behavioral Sciences (PJR, PAA), University of Washington, Seattle, WA; and the Weill Cornell Institute of Geriatric Psychiatry (GSA), Weill Cornell Medicine, White Plains, NY.
Yiqun T ChenDepartment of Psychology (MSS, BNR), University of Nevada, Las Vegas, NV; Department of Psychiatry (MSS), McLean Hospital, Belmont, MA; Data Science Institute and Department of Biomedical Data Science (YTC), Stanford University, Stanford, CA; Department of Psychiatry and Behavioral Sciences (PJR, PAA), University of Washington, Seattle, WA; and the Weill Cornell Institute of Geriatric Psychiatry (GSA), Weill Cornell Medicine, White Plains, NY.
Patrick J RaueDepartment of Psychology (MSS, BNR), University of Nevada, Las Vegas, NV; Department of Psychiatry (MSS), McLean Hospital, Belmont, MA; Data Science Institute and Department of Biomedical Data Science (YTC), Stanford University, Stanford, CA; Department of Psychiatry and Behavioral Sciences (PJR, PAA), University of Washington, Seattle, WA; and the Weill Cornell Institute of Geriatric Psychiatry (GSA), Weill Cornell Medicine, White Plains, NY.
Patricia A AreánDepartment of Psychology (MSS, BNR), University of Nevada, Las Vegas, NV; Department of Psychiatry (MSS), McLean Hospital, Belmont, MA; Data Science Institute and Department of Biomedical Data Science (YTC), Stanford University, Stanford, CA; Department of Psychiatry and Behavioral Sciences (PJR, PAA), University of Washington, Seattle, WA; and the Weill Cornell Institute of Geriatric Psychiatry (GSA), Weill Cornell Medicine, White Plains, NY.
George S AlexopoulosDepartment of Psychology (MSS, BNR), University of Nevada, Las Vegas, NV; Department of Psychiatry (MSS), McLean Hospital, Belmont, MA; Data Science Institute and Department of Biomedical Data Science (YTC), Stanford University, Stanford, CA; Department of Psychiatry and Behavioral Sciences (PJR, PAA), University of Washington, Seattle, WA; and the Weill Cornell Institute of Geriatric Psychiatry (GSA), Weill Cornell Medicine, White Plains, NY.
Brenna N RennDepartment of Psychology (MSS, BNR), University of Nevada, Las Vegas, NV; Department of Psychiatry (MSS), McLean Hospital, Belmont, MA; Data Science Institute and Department of Biomedical Data Science (YTC), Stanford University, Stanford, CA; Department of Psychiatry and Behavioral Sciences (PJR, PAA), University of Washington, Seattle, WA; and the Weill Cornell Institute of Geriatric Psychiatry (GSA), Weill Cornell Medicine, White Plains, NY.

Funding

Outreach/Diversity/Pipeline ProjectP20GM103440 · NIGMS · UNIVERSITY OF NEVADA RENO · PI Eduardo A Robleto · 2012 to 2026
$58.0M
UW ALACRITY Center for Psychosocial Interventions ResearchP50MH115837 · NIMH · UNIVERSITY OF WASHINGTON · PI IAN Moore BENNETT · 2018 to 2026
$18.2M
Relief: A Behavioral Intervention for Depression and Chronic Pain for Primary Care PracticesP50MH113838 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI SIREY, JO ANNE · 2017 to 2020
$5.7M
Target engagement of a reward exposure therapy (Engage) for late life depressionR01MH102252 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2014 to 2018
$2.0M
2/2 Stepped, reward-exposure based therapy vs. PST in late life depressionR01MH102304 · NIMH · UNIVERSITY OF WASHINGTON · PI AREAN, PATRICIA A. · 2014 to 2018
$1.7M
NIGMS NIH HHS P20 GM103440NIMH NIH HHS P50 MH113838NIMH NIH HHS P50 MH115837NIMH NIH HHS R01 MH102252NIMH NIH HHS R01 MH102304
6 · The paper itself

Abstract

Objectives: Executive dysfunction is common in later-life depression (LLD). This study examined whether: 1) executive function predicts change in depressive symptoms during brief psychotherapy and 2) performance on cognitive tests changes during psychotherapy. Design: Post hoc analysis of a noninferiority randomized clinical trial comparing 9 weekly sessions of problem-solving therapy (PST) and Engage, a streamlined psychotherapy for depression. Setting: Two-site trial at academic medical centers in Seattle, WA and New York, NY. Participants: Measurements: Cognitive measures included the Iowa Gambling Task (IGT), Wisconsin Card Sorting Test (WCST), Stroop test, Digit Span, and Hopkins Verbal Learning Test (HVLT-R). Treatment outcomes consisted of longitudinal assessment using the Hamilton Depression Rating Scale (HAM-D) and World Health Organization Disability Assessment Schedule 2.0 (WHODAS). Results: Conclusions: Baseline cognitive functions, including executive function, did not influence reduction in depressive symptoms during brief psychotherapies. Brief psychotherapies may improve aspects of executive function such as decision-making related to reward. ClinicalTrialsgov Identifier: NCT0208G201.

Indexed as

Cognitive functionolder adultspsychotherapytreatment response

Identifiers

PMID41306470
PMCPMC12646658

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.