ArticleJournal of diabetes and metabolic disorders2025
Therapeutic potential of pectin from various sources against diabetes mellitus in rats: AKT/PI3K/GSK-3β/CREB signaling pathways, inflammation, oxidative stress and genotoxicity crosstalk.
Article in Journal of diabetes and metabolic disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Prohibitive Effects of ω-3 on Pancreatic Damage in an Experimental Diabetes Model: Blood Glucose, Insulin, Lipid Profiles, Oxidative Stress, Inflammation, Pancreatic Tissue Morphology, and Apoptotic Pathways.Journal of biochemical and molecular toxicology · 2026Article
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11 authors.
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Abstract
Background: Diabetes mellitus type 2 (DMT2) is a chronic metabolic disorder caused by a disruption or resistance in insulin secretion. AKT /PI3K, GSK-3β and CREB signaling pathways influence insulin sensitivity and glucose metabolism. Purpose: This study aimed to compare the therapeutic impact of pectin extracted from different sources (lemon, orange and grapefruit peels) against diabetic rats. Methods: Fourier transform infrared spectroscopy (FT-RI) and Proton Nuclear Magnetic Resonance ( Results: The FT-IR and Conclusion: Pectin extracted from lemon, orange and grapefruit peels showed a promising therapeutic impact against DMT2. High degree of esterification in lemon pectin may explore its potent effect Graphical Abstract:
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