Evidence map›Paper›PMID 41306382›Full record

ArticleJournal of surgical case reports2025

From chronic hidradenitis suppurativa to epidermoid carcinoma, from inflammation to cellular degeneration.

Saúl Sánchez Iglesias, Cristina de la Cruz Cuadrado, Julián de Pedro Conal

Abstract readCase Reports
In one paragraph

Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Saúl Sánchez IglesiasHospital Universitario de Toledo, Avenida del Río Guadiana, Toledo 45007, Spain.ORCID https://orcid.org/0009-0007-9215-6801
Cristina de la Cruz CuadradoHospital Universitario de Toledo, Avenida del Río Guadiana, Toledo 45007, Spain.
Julián de Pedro ConalHospital Universitario de Toledo, Avenida del Río Guadiana, Toledo 45007, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hidradenitis suppurativa is a chronic inflammatory skin disease characterized by recurrent nodules, abscesses, and sinus tracts, most often located in axillary, inguinal, and gluteal regions. Malignant transformation into squamous cell carcinoma is a rare but serious complication. We present the case of a 50-year-old man with ˃10 years of poorly controlled hidradenitis suppurativa who developed painful gluteal discharge and multiple exophytic lesions. Imaging demonstrated large perianal and perineal masses with destruction of the coccyx, but no distant spread. Biopsy confirmed well-differentiated squamous cell carcinoma. Because of the local extent, the multidisciplinary team recommended radiotherapy as the primary treatment. Malignant degeneration of hidradenitis suppurativa is more frequent in long-standing, advanced disease, particularly in gluteal and perineal areas, and is associated with delayed diagnosis and high mortality. Early biopsy of suspicious lesions and multidisciplinary management are essential to improve prognosis.

Indexed as

case reporthidradenitis suppurativasquamous cell carcinoma

Identifiers

PMID41306382
PMCPMC12646241

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.