Evidence map›Paper›PMID 41306358›Full record

ArticleMalawi medical journal : the journal of Medical Association of Malawi2025

Characterization of Mycobacterium Tuberculosis (MTB)-Positive Individuals within the Healthcare Catchment Area of Mzuzu Central Hospital, Malawi.

Ning Zhang, Thomas Stuart Mughogho, Rashid Kaseka, Dokani Michael Ndovi, Zhonglin Wang, Jian Hu, Xiaoqin Wang

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Article in Malawi medical journal : the journal of Medical Association of Malawi, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ning ZhangDepartment of Clinical Laboratory, The First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi Province, China.
Thomas Stuart MughoghoLaboratory Department, Mzuzu Central Hospital, Luwinga, Mzuzu 2, Malawi.
Rashid KasekaLaboratory Department, Mzuzu Central Hospital, Luwinga, Mzuzu 2, Malawi.
Dokani Michael NdoviLaboratory Department, Mzuzu Central Hospital, Luwinga, Mzuzu 2, Malawi.
Zhonglin WangDepartment of Clinical Laboratory, The First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi Province, China.
Jian HuDepartment of Clinical Laboratory, The First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi Province, China.
Xiaoqin WangDepartment of Clinical Laboratory, The First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi Province, China.

Funding

Science and Technology Program of Xi'an 24LLRHZDZX0028
6 · The paper itself

Abstract

Purpose: To investigate the characteristics of the Mycobacterium tuberculosis (MTB)-positive population within the healthcare service area of Mzuzu Central Hospital in Malawi, with the objective of providing a scientific foundation for tuberculosis (TB) prevention and control strategies in the region. Methods: This retrospective study encompassed 4,711 patients who underwent GeneXpert (GeneXpert MTB/RIF or GeneXpert MTB/RIF Ultra) testing. Data on laboratory results, demographics, HIV status, and residential addresses were analyzed. Results: Among 4,711 patients, 424 (9%) tested MTB-positive. A strong correlation was observed between MTB and HIV infection, as HIV/TB co-infection accounted for 47.9% of MTB-positive cases (χ Conclusion: Within the healthcare catchment area of Mzuzu Central Hospital, MTB infection is significantly associated with HIV. Males show a higher MTB positivity rate than females. The study identifies high-risk age groups, temporal trends, and geographical TB patterns. Rifampicin resistance is a critical issue needing urgent attention.

Indexed as

HIV InfectionsMycobacterium tuberculosisTuberculosisAdolescentAdultAgedAge DistributionCatchment Area, HealthChildChild, PreschoolCoinfectionFemaleHumansMalawiMaleMiddle AgedRifampinDemographics distributionGeneXpert MTB/RIF UltraHIV/TB co-infectionMycobacterium tuberculosisRifampicin resistance

Identifiers

PMID41306358
PMCPMC12153221

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.