ArticleCureus2025
Spinal Muscular Atrophy in Colombia: Nationwide Incidence, Demographic Distribution, and Healthcare Challenges.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSpinal muscular atrophy (SMA) is a genetic neuromuscular disorder marked by progressive motor neuron degeneration, leading to muscle weakness and atrophy. Although rare, SMA severely impacts morbidity and quality of life, especially through respiratory complications. Limited data on SMA in Colombia hampers healthcare planning, emphasizing the need for region-specific studies to guide resource allocation and policy development.
methodsThis descriptive, longitudinal study analyzed SMA incidence in Colombia from 2016 to 2024, using data from the National Public Health Surveillance System (SIVIGILA) and the Health Services Information System (RIPS). Incidence rates were calculated per 100,000 live births, focusing particularly on SMA type 1. Temporal trends and subgroup distributions (by gender and geographic region) were examined using descriptive statistics.
resultsSMA incidence showed an upward trend, peaking in 2019 at 8.43 per 100,000 live births before stabilizing. SMA type 1 cases, representing the most severe form, accounted for a significant proportion, highlighting the intensive healthcare demands associated with this subtype. Geographic disparities in incidence were observed, with higher rates in regions with greater healthcare access, suggesting variability in diagnostic and reporting practices across Colombia.
conclusionThis study offers critical insights into SMA's epidemiology in Colombia, underscoring the healthcare burden of SMA type 1 and regional disparities in case reporting. Findings support the need for improved SMA surveillance, targeted resources in high-incidence regions, and possible implementation of newborn screening to enhance early diagnosis and care. These actions are essential for aligning SMA management in Colombia with international standards and addressing healthcare inequities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.