ReviewCureus2025
Associations Between Dermatoglyphic Patterns and Oral Diseases in Children: A Systematic Review and Meta-Analysis.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Dermatoglyphic patterns as predictors of dental pain perception.Bioinformation · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dermatoglyphics - the scientific study of epidermal ridge patterns - develops during the same embryonic period as the oral-craniofacial complex and remains unchanged throughout life. Because of this developmental parallelism, dermatoglyphic traits have been explored as potential non-invasive associations of oral diseases in children. This systematic review and meta-analysis, conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines (PROSPERO ID: CRD42022322563), evaluated associations between dermatoglyphic features and three pediatric oral conditions: dental caries, malocclusion, and nonsyndromic cleft lip and/or palate (NSCL/P). Electronic searches across Medline, Ovid, Cochrane CENTRAL, and Google Scholar (January 1990-August 2025) identified cross-sectional and case-control studies with ≥ 200 participants assessing qualitative (loops, whorls, arches) and quantitative (atd angle, ridge counts) traits. Fifteen studies comprising approximately 7,300 children were included; 12 contributed to quantitative synthesis and nine to meta-analysis. In dental caries cohorts, pooled percentage-point differences showed that whorls were more frequent in affected children (mean difference (MD): 6.86; 95% CI: 6.67-7.05; p < 0.01; I² = 90), whereas loops were less frequent (MD: -6.41; 95% CI: -6.56 to -6.26; p < 0.01; I² = 98); arches showed smaller but significant variation (MD: -0.26; 95% CI: -0.49 to -0.04; p = 0.04). In NSCL/P studies, lower total ridge count, higher a-b ridge counts, and greater fluctuating asymmetry were observed (p < 0.001). Malocclusion investigations demonstrated class-specific pattern shifts with inconsistent significance. Substantial heterogeneity (I² ≈ 78-98%) and moderate methodological quality were observed. Collectively, dermatoglyphic traits - particularly whorls, loops, and atd angles - show possible associations with pediatric oral conditions. Although not diagnostic, these traits may serve as low-cost indicators warranting validation through large, multicenter, and longitudinal studies while considering potential publication bias, limited representativeness, and geographic concentration of existing evidence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.