ArticleCureus2025
A Diagnostic Pitfall: Retrocaval Nerve Sheath Tumor.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 78-year-old female with a history of resected colorectal adenocarcinoma presented with progressively rising serum carcinoembryonic antigen (CEA) levels since 2022. An August 2023Positron Emission Tomography/Computed Tomography (PET-CT) revealed a 1.4 cm fluorodeoxyglucose (FDG)-avid retrocaval lesion, initially raising suspicion for metastatic lymphadenopathy given her cancer history. Despite receiving stereotactic body radiotherapy and remaining asymptomatic, her CEA levels continued to climb, and the lesion mildly enlarged to 1.8 cm by November 2024. This persistent elevation and lesion growth necessitated a definitive tissue diagnosis. Subsequent biopsy showed a spindle cell neoplasm. Immunohistochemical staining, crucial for characterizing soft-tissue tumor differentiation, revealed diffuse positivity for SOX10 and S100 protein, consistent with a primary nerve sheath tumor rather than metastatic disease. This case highlights the diagnostic challenge posed by FDG-avid lesions in patients with a history of malignancy, underscoring the importance of considering rare differential diagnoses and pursuing tissue diagnosis when imaging is equivocal or clinical presentation deviates from expected metastatic behavior.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.